E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study

Vanishree B, Amirunnisa Begum.

Abstract
Background: Overdose is defined as any substance that is exposed excessively, which is intended for consumption. There are many drugs which are used therapeutically, but sometimes self-harm can be done with medications such as analgesics, antiepileptics, and sedatives. The high mortality and morbidity associated with drug overdose could be due to various factors such as easy availability, improper regulations for dispensing drugs, lack of control for over the counter drugs.

Aim and Objective: The purpose of this study is to document the incidence of drug overdose cases, sociodemographic characteristics, and its management in a tertiary care hospital.

Materials and Methods: A prospective, observational study was conducted from January 2014 to December 2014 at Casualty and Medicine Department in a tertiary care hospital.

Results: A total of 61 cases were included in the study. Drug overdose cases were seen in the age group of 21–30 years (67.2%). Intentional drug overdose is seen in 58 (95.08%) cases. In this study, 34.4% of patients presented to the hospital within 6 h of event. Paracetamol was the most common (32.7%). In most of the paracetamol overdose, cases were treated with N-acetyl cysteine, phenobarbitone overdose with forced alkaline diuresis, benzodiazepines overdose with flumazenil, and opioids overdose with naloxone. This study shows that 93.3% of patients had an uncomplicated course of stay in hospital.

Conclusion: Drug overdose is a major public health concern in the society. The most vulnerable population in the society is the younger age group. Prevention strategies should be dealt in this high risk group.

Key words: Drug overdose, Paracetamol, Treatment outcomes


 
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Pubmed Style

B V, Begum A. Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study. Natl J Physiol Pharm Pharmacol. 2022; 12(11): 1811-1815. doi:10.5455/njppp.2022.12.03099202212032022


Web Style

B V, Begum A. Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study. https://www.njppp.com/?mno=96747 [Access: November 24, 2022]. doi:10.5455/njppp.2022.12.03099202212032022


AMA (American Medical Association) Style

B V, Begum A. Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study. Natl J Physiol Pharm Pharmacol. 2022; 12(11): 1811-1815. doi:10.5455/njppp.2022.12.03099202212032022



Vancouver/ICMJE Style

B V, Begum A. Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study. Natl J Physiol Pharm Pharmacol. (2022), [cited November 24, 2022]; 12(11): 1811-1815. doi:10.5455/njppp.2022.12.03099202212032022



Harvard Style

B, V. & Begum, . A. (2022) Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study. Natl J Physiol Pharm Pharmacol, 12 (11), 1811-1815. doi:10.5455/njppp.2022.12.03099202212032022



Turabian Style

B, Vanishree, and Amirunnisa Begum. 2022. Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (11), 1811-1815. doi:10.5455/njppp.2022.12.03099202212032022



Chicago Style

B, Vanishree, and Amirunnisa Begum. "Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1811-1815. doi:10.5455/njppp.2022.12.03099202212032022



MLA (The Modern Language Association) Style

B, Vanishree, and Amirunnisa Begum. "Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study." National Journal of Physiology, Pharmacy and Pharmacology 12.11 (2022), 1811-1815. Print. doi:10.5455/njppp.2022.12.03099202212032022



APA (American Psychological Association) Style

B, V. & Begum, . A. (2022) Management and outcome of different drug overdose cases in a tertiary care hospital – A prospective observational study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (11), 1811-1815. doi:10.5455/njppp.2022.12.03099202212032022