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Original Research 


Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital

Swetha K, Shailendar Singh, Jyothi D B.

Abstract
Background: Pediatric diarrhea is one of the major causes of childhood mortality around the world. Oral rehydrationtherapy (ORT) along with zinc supplementation can reduce the irrational antimicrobial use and stay in hospital.

Aims and Objectives: This study aims to evaluate the role of zinc in reduction of stool frequency and duration of diarrheal episode.

Materials and Methods: A prospective observational study was performed for 12 months at pediatric in-patient unit of BRIMS teaching hospital, Bidar. We evaluated 400 prescriptions of acute diarrhea cases for the role of zinc based on reduction of stool frequency and decrease in the duration of diarrheal episode.

Results: A study revealed a very statistically significant reduction (P < 0.001) in both stool frequencies during the 3rd–5th day and there was reduction in mean duration of diarrheal episode in the group treated with ORT/parenteral rehydration+ zinc.

Conclusion: We observed significant decrease in both stool frequency and mean duration of diarrheal episodes in the group treated with ORT/parenteral rehydration+ zinc as compared to ORT/parenteral rehydration alone. Thus, we recommend practitioners to use ORS and zinc which reduces the stay in hospital and helps in faster recovery. And also, it would definitely reduce the practice of polypharmacy and inappropriate antibiotic prescribing practices.

Key words: Acute Diarrhea; Children; ORS; Zinc; World Health Organization; Indian Academic of Pediatrics


 
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Pubmed Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol. 2022; 12(8): 1160-1163. doi:10.5455/njppp.2022.12.12462202129122021


Web Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. https://www.njppp.com/?mno=80242 [Access: August 03, 2022]. doi:10.5455/njppp.2022.12.12462202129122021


AMA (American Medical Association) Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol. 2022; 12(8): 1160-1163. doi:10.5455/njppp.2022.12.12462202129122021



Vancouver/ICMJE Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol. (2022), [cited August 03, 2022]; 12(8): 1160-1163. doi:10.5455/njppp.2022.12.12462202129122021



Harvard Style

K, S., Singh, . S. & B, . J. D. (2022) Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol, 12 (8), 1160-1163. doi:10.5455/njppp.2022.12.12462202129122021



Turabian Style

K, Swetha, Shailendar Singh, and Jyothi D B. 2022. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. National Journal of Physiology, Pharmacy and Pharmacology, 12 (8), 1160-1163. doi:10.5455/njppp.2022.12.12462202129122021



Chicago Style

K, Swetha, Shailendar Singh, and Jyothi D B. "Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1160-1163. doi:10.5455/njppp.2022.12.12462202129122021



MLA (The Modern Language Association) Style

K, Swetha, Shailendar Singh, and Jyothi D B. "Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital." National Journal of Physiology, Pharmacy and Pharmacology 12.8 (2022), 1160-1163. Print. doi:10.5455/njppp.2022.12.12462202129122021



APA (American Psychological Association) Style

K, S., Singh, . S. & B, . J. D. (2022) Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. National Journal of Physiology, Pharmacy and Pharmacology, 12 (8), 1160-1163. doi:10.5455/njppp.2022.12.12462202129122021