E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat

Rakesh Patel, Khushi Joshi, Heeta Mehta.

Abstract
Background: During pregnancy, hemodilution of plasma volume leads to reduction in platelets count by approximately 6–7% during 3rd trimester. Pregnant women with thrombocytopenia have higher risk of bleeding excessively during pregnancy, labor, and puerperium. The present study focuses on fetomaternal outcome among pregnant women having thrombocytopenia.

Aims and Objectives: This study aims to study the incidence of thrombocytopenia in pregnancy, to identify various factors responsible for thrombocytopenia in pregnancy, and to evaluate fetomaternal outcome in patients with thrombocytopenia in pregnancy.

Materials and Methods: A prospective study was conducted in the department of obstetrics and gynecology at tertiary care center of Ahmedabad. A total of 96 cases of thrombocytopenia in pregnancy were included in the study. Fetomaternal outcome was assessed among the study participants.

Results: The incidence of thrombocytopenia in the present study was 0.77%. Obstetric causes (53.12%) accounted for most common cause of thrombocytopenia, followed by gestational thrombocytopenia (27.08%), dengue (10.41%), malaria (4.16%), and immune thrombocytopenia (4.16%). Postpartum hemorrhage (15.62%), eclampsia (14.58%), disseminated intravascular coagulation (11.45%), and abruption (8.33%) were the most common maternal complications. The most common neonatal complication was prematurity (67.7%) followed by intrauterine growth retardation (23.95%) and birth asphyxia (9.3%).

Conclusion: Hypertensive disorders of pregnancy including severe preeclampsia, eclampsia, and HELLP syndrome are found to be the most common cause of thrombocytopenia followed by gestational thrombocytopenia and infectious causes. The present study widened the spectrum of the causes for thrombocytopenia in pregnant women. Gestational thrombocytopenia is associated with mild-to-moderate thrombocytopenia and hardly having any complications.

Key words: Fetomaternal Outcome; Thrombocytopenia; Pregnancy


 
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Pubmed Style

Patel R, Joshi K, Mehta H. Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat. Natl J Physiol Pharm Pharmacol. 2022; 12(8): 1282-1286. doi:10.5455/njppp.2022.12.07336202207072022


Web Style

Patel R, Joshi K, Mehta H. Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat. https://www.njppp.com/?mno=78835 [Access: August 03, 2022]. doi:10.5455/njppp.2022.12.07336202207072022


AMA (American Medical Association) Style

Patel R, Joshi K, Mehta H. Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat. Natl J Physiol Pharm Pharmacol. 2022; 12(8): 1282-1286. doi:10.5455/njppp.2022.12.07336202207072022



Vancouver/ICMJE Style

Patel R, Joshi K, Mehta H. Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat. Natl J Physiol Pharm Pharmacol. (2022), [cited August 03, 2022]; 12(8): 1282-1286. doi:10.5455/njppp.2022.12.07336202207072022



Harvard Style

Patel, R., Joshi, . K. & Mehta, . H. (2022) Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat. Natl J Physiol Pharm Pharmacol, 12 (8), 1282-1286. doi:10.5455/njppp.2022.12.07336202207072022



Turabian Style

Patel, Rakesh, Khushi Joshi, and Heeta Mehta. 2022. Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat. National Journal of Physiology, Pharmacy and Pharmacology, 12 (8), 1282-1286. doi:10.5455/njppp.2022.12.07336202207072022



Chicago Style

Patel, Rakesh, Khushi Joshi, and Heeta Mehta. "Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1282-1286. doi:10.5455/njppp.2022.12.07336202207072022



MLA (The Modern Language Association) Style

Patel, Rakesh, Khushi Joshi, and Heeta Mehta. "Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat." National Journal of Physiology, Pharmacy and Pharmacology 12.8 (2022), 1282-1286. Print. doi:10.5455/njppp.2022.12.07336202207072022



APA (American Psychological Association) Style

Patel, R., Joshi, . K. & Mehta, . H. (2022) Fetomaternal outcome in pregnancy with thrombocytopenia: A prospective study from one of the teaching health-care institutes of Ahmedabad, Gujarat. National Journal of Physiology, Pharmacy and Pharmacology, 12 (8), 1282-1286. doi:10.5455/njppp.2022.12.07336202207072022