Abstract
Background:
Postpartum depression is a serious issue affecting society as a whole. While it typically subsides in most women, it can persist in some cases. This condition is particularly concerning because of its effects on the mother, her long-term relationships, and the family. Of special concern is its impact on the mother-infant relationship, which can, in turn, influence infant development.

Methods:
This hospital-based cross-sectional study was conducted during 2019–2020 covering a population of 355 postpartum women in postnatal clinics. In addition to the structured interview schedule, The Edinburgh Postnatal Depression Scale was used to evaluate the extent of depression. Logistic regression was used to evaluate the independent effects of various socio-clinical variables.

Results:
The prevalence rate of postnatal depression was 23.0%. Statistically significant risk factors included maternal age >25 years, lower socioeconomic status, nuclear family background, conception through assisted reproductive technology, and history of abortion.

Conclusion:
The prevalence of Postpartum depression was high in the study population. There were multiple factors associated with its development, which required early screening and intervention.

Recommendation:
Special counseling sessions and health promotion activities at the institutional level can mitigate postnatal depression.

Key words: Postpartum depression, Socio clinical variables, Screening, intervention