E-ISSN 2231-3206 | ISSN 2320-4672
 

Case Series

Online Publishing Date:
01 / 04 / 2023

 


Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series

Namita Mohanty, Medimi Nageswar, Sangeeta Rout, Soumyaranjan Mishra.


Abstract
Sjogren’s syndrome is a chronic and slowly progressing autoimmune disease characterized by lyphocytic infiltration of exocrine glands resulting in Sicca syndrome (xerostomia and keratocunjuntivitis sicca). The disease can present alone or along with other autoimmune diseases leading to significant organ specific and systemic disease. Middle aged women (Female: Male: 9:1) are primarily affected. Extraglandular (systemic) manifestations are seen in one third of patients with Sjogren’s syndrome. Among the extraglandular manifestations, renal involvement is commonly seen. Renal involvement in the form of tubulointerstitial nephritis (TIN) is more common compared to glomerular involvement. Distal renal tubular acidosis (RTA) is more common manifestation of TIN presenting as mild hypokalemia, metabolic acidosis, and rarely with hypokalemic periodic paralysis. We report three cases of hypokalemic periodic paralysis with metabolic acidosis, two in respiratory paralysis, diagnosed as distal RTA. On further evaluation of distal RTA, the patient diagnosed to have Sjogren’s syndrome and managed accordingly. Our report shows that Sjogren’s syndrome is a rare but important cause of hypokaemic periodic paralysis due to RTA.

Key words: Sjogren’s Syndrome; Renal Tubular Acidosis; Hypokalemia


 
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How to Cite this Article
Pubmed Style

Mohanty N, Nageswar M, Rout S, Mishra S. Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 1133-1135. doi:10.5455/njppp.2023.13.0312502321032023


Web Style

Mohanty N, Nageswar M, Rout S, Mishra S. Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series. https://www.njppp.com/?mno=145646 [Access: March 15, 2024]. doi:10.5455/njppp.2023.13.0312502321032023


AMA (American Medical Association) Style

Mohanty N, Nageswar M, Rout S, Mishra S. Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 1133-1135. doi:10.5455/njppp.2023.13.0312502321032023



Vancouver/ICMJE Style

Mohanty N, Nageswar M, Rout S, Mishra S. Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series. Natl J Physiol Pharm Pharmacol. (2023), [cited March 15, 2024]; 13(5): 1133-1135. doi:10.5455/njppp.2023.13.0312502321032023



Harvard Style

Mohanty, N., Nageswar, . M., Rout, . S. & Mishra, . S. (2023) Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series. Natl J Physiol Pharm Pharmacol, 13 (5), 1133-1135. doi:10.5455/njppp.2023.13.0312502321032023



Turabian Style

Mohanty, Namita, Medimi Nageswar, Sangeeta Rout, and Soumyaranjan Mishra. 2023. Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 1133-1135. doi:10.5455/njppp.2023.13.0312502321032023



Chicago Style

Mohanty, Namita, Medimi Nageswar, Sangeeta Rout, and Soumyaranjan Mishra. "Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 1133-1135. doi:10.5455/njppp.2023.13.0312502321032023



MLA (The Modern Language Association) Style

Mohanty, Namita, Medimi Nageswar, Sangeeta Rout, and Soumyaranjan Mishra. "Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series." National Journal of Physiology, Pharmacy and Pharmacology 13.5 (2023), 1133-1135. Print. doi:10.5455/njppp.2023.13.0312502321032023



APA (American Psychological Association) Style

Mohanty, N., Nageswar, . M., Rout, . S. & Mishra, . S. (2023) Sjogren’s syndrome presenting as hypokalemic periodic paralysis, a rare manifestation: A case series. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 1133-1135. doi:10.5455/njppp.2023.13.0312502321032023