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Original Research
Online Published: 22 Mar 2023
 


Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai

Hemalatha P, Prince Johnson Samuel.


Abstract
Background: The incidence and prevalence of hypertension have been increasing steadily in the present era. Inflammation is a proven key factor in the pathogenesis of hypertension. C-reactive protein (CRP) is a known marker of vascular inflammation leading to hypertension. High-sensitivity CRP (hs-CRP) is a sensitive marker of assessment of inflammatory changes before the rise in CRP.

Aims and Objectives: The goal of this study was to decipher the stage at which inflammation starts related to changes in hypertension using CRP as well as hs-CRP.

Materials and Methods: This is a cross-sectional study which included 120 individuals, who were subdivided into three groups - Normotensive: 40, pre-hypertensive: 40, and hypertensive. JNC classification was used for the categorization of blood pressure. hs-CRP was analyzed as per the principle of ELISA.

Results: There was a significant difference in hs-CRP between normotensive and hypertensive. A strong association between hypertension, CRP, and hs-CRP was found.

Conclusion: hs-CRP is a sensitive marker for early assessment of inflammatory components in hypertension.

Key words: Pre-hypertensive; Hypertensive; C-reactive Protein; High-sensitivity C-reactive Protein


 
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Pubmed Style

P H, Samuel PJ. Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai. Natl J Physiol Pharm Pharmacol. 2023; 13(4): 872-875. doi:10.5455/njppp.2023.13.11554202215032023

Web Style

P H, Samuel PJ. Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai. https://www.njppp.com/?mno=130996 [Access: March 08, 2025]. doi:10.5455/njppp.2023.13.11554202215032023

AMA (American Medical Association) Style

P H, Samuel PJ. Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai. Natl J Physiol Pharm Pharmacol. 2023; 13(4): 872-875. doi:10.5455/njppp.2023.13.11554202215032023


Vancouver/ICMJE Style

P H, Samuel PJ. Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai. Natl J Physiol Pharm Pharmacol. (2023), [cited March 08, 2025]; 13(4): 872-875. doi:10.5455/njppp.2023.13.11554202215032023


Harvard Style

P, H. & Samuel, . P. J. (2023) Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai. Natl J Physiol Pharm Pharmacol, 13 (4), 872-875. doi:10.5455/njppp.2023.13.11554202215032023


Turabian Style

P, Hemalatha, and Prince Johnson Samuel. 2023. Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai. National Journal of Physiology, Pharmacy and Pharmacology, 13 (4), 872-875. doi:10.5455/njppp.2023.13.11554202215032023


Chicago Style

P, Hemalatha, and Prince Johnson Samuel. "Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 872-875. doi:10.5455/njppp.2023.13.11554202215032023


MLA (The Modern Language Association) Style

P, Hemalatha, and Prince Johnson Samuel. "Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai." National Journal of Physiology, Pharmacy and Pharmacology 13.4 (2023), 872-875. Print. doi:10.5455/njppp.2023.13.11554202215032023


APA (American Psychological Association) Style

P, H. & Samuel, . P. J. (2023) Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai. National Journal of Physiology, Pharmacy and Pharmacology, 13 (4), 872-875. doi:10.5455/njppp.2023.13.11554202215032023


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