E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study

Shweta Akhani, S R Gotmare.

Abstract
Background: High cholesterol is the sixth-highest risk factor for death in the globe. Herbal medications regularly complement modern medical care, especially by providing safe and well-tolerated therapies for chronic conditions.

Aims and Objectives: The present study was undertaken to evaluate and compare cholesterol lowering effects of Terminalia arjuna bark and Bacopa monnieri leaves (Brahmi) extract in human blood samples diagnosed with hyperlipidemia.

Materials and Methods: Herbal extract of arjuna (T. arjuna) and Brahmi (B. monnieri) leaves in distilled water (d/w) and cow’s urine (c/u) [A1, A2, B1, B2] was taken and added to the pooled serum samples collected aseptically and a kinetic study was performed with it. Cholesterol standard was obtained from Erba chem Transasia kit (Trinder’s method, endpoint) with standard cutoff value 200 mg/dL.

Results: Baseline reading of total cholesterol in all samples was 189 mg/dL. After 2 h, total cholesterol reading in A1 was 159 mg/dL, 157, 155 and 154 mg/dL in A2, B1, B2, respectively. After 4 h, total cholesterol reading in A1 was 149 mg/dL, 148, 146, and 144 mg/dL in A2, B1, B2, respectively. After 6 h, total cholesterol reading in A1 was 109 mg/dL, 104, 112, and 110 mg/dL in A2, B1, B2, respectively.

Conclusion: From the findings of the present study, it was found that aqueous extract of Brahmi (B. monnieri) and T. arjuna (Arjuna) were effective in reducing total cholesterol levels. It can be considered as a potential therapeutic alternative in patients with hyperlipidemia, but warrants further clinical studies.

Key words: Cholestrol; Serum; Brahmi; Arjuna; Hypolipidemic


 
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How to Cite this Article
Pubmed Style

Akhani S, Gotmare SR. Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 1088-1091. doi:10.5455/njppp.2023.13.11542202208042023


Web Style

Akhani S, Gotmare SR. Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study. https://www.njppp.com/?mno=129538 [Access: February 03, 2024]. doi:10.5455/njppp.2023.13.11542202208042023


AMA (American Medical Association) Style

Akhani S, Gotmare SR. Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 1088-1091. doi:10.5455/njppp.2023.13.11542202208042023



Vancouver/ICMJE Style

Akhani S, Gotmare SR. Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study. Natl J Physiol Pharm Pharmacol. (2023), [cited February 03, 2024]; 13(5): 1088-1091. doi:10.5455/njppp.2023.13.11542202208042023



Harvard Style

Akhani, S. & Gotmare, . S. R. (2023) Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study. Natl J Physiol Pharm Pharmacol, 13 (5), 1088-1091. doi:10.5455/njppp.2023.13.11542202208042023



Turabian Style

Akhani, Shweta, and S R Gotmare. 2023. Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 1088-1091. doi:10.5455/njppp.2023.13.11542202208042023



Chicago Style

Akhani, Shweta, and S R Gotmare. "Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 1088-1091. doi:10.5455/njppp.2023.13.11542202208042023



MLA (The Modern Language Association) Style

Akhani, Shweta, and S R Gotmare. "Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study." National Journal of Physiology, Pharmacy and Pharmacology 13.5 (2023), 1088-1091. Print. doi:10.5455/njppp.2023.13.11542202208042023



APA (American Psychological Association) Style

Akhani, S. & Gotmare, . S. R. (2023) Hypolipidemic effect of Bacopa monnieri (Brahmi) and Terminalia arjuna (Arjuna): An in vitro study. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 1088-1091. doi:10.5455/njppp.2023.13.11542202208042023