Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?

Kalyani Praba P; Vineetha V S; Bhavsar Nikhil Rajendra; Saravanan A; Thamarai Selvi K; Prabhavathi K

doi:10.5455/njppp.2022.12.094592022014102022

2023, Vol: 13, Issue: 3

13/3Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

Authorship Declaration

« Previous Article

Original Research

Natl J Physiol Pharm Pharmacol. 2022; 12(11): 1875-1879

doi: 10.5455/njppp.2022.12.094592022014102022

Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?

Kalyani Praba P, Vineetha V S, Bhavsar Nikhil Rajendra, Saravanan A, Thamarai Selvi K, Prabhavathi K.

Abstract
Background: Periodontitis and type 2 diabetes (T2D) are common public health problems affecting people worldwide, and both are involved in renal dysfunction. Serum creatinine (SCr) is an important marker for renal diseases. The recent study found that diabetes is associated with lower SCr value. In contrast, periodontitis was associated with both low and high SCr concentration and renal impairment.

Aims and Objectives: The objective of our study is to explore the interconnection and correlation among periodontitis and renal disease in T2D mellitus patients.

Materials and Methods: The study included 90 subjects aged 30–65. We assessed PD status through a standardized community periodontal index (CPI). We conducted hematological investigations to assess SCr, fasting blood glucose, postprandial blood glucose, and glycated hemoglobin. The study population was organized into four groups: Group 1 (healthy), Group 2 (PD only), Group 3 (T2D only), and Group 4 (PD and T2D). We used Pearson’s correlation, and P ˂ 0.05 was considered statistically significant.

Results: SCr was positively correlated with T2D parameters and inversely correlated with PD. A significant correlation was found with higher SCr values in Group 4 than in other study groups.

Conclusion: PD has a plausible association and synergistic effect of causing renal diseases in patients with T2D.

Key words: Periodontitis; Serum Creatinine Level; Type 2 Diabetes Mellitus

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Kalyani Praba P Articles by Vineetha V S Articles by Bhavsar Nikhil Rajendra Articles by Saravanan A Articles by Thamarai Selvi K Articles by Prabhavathi K
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

P KP, S VV, Rajendra BN, A S, K TS, K P. Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?. Natl J Physiol Pharm Pharmacol. 2022; 12(11): 1875-1879. doi:10.5455/njppp.2022.12.094592022014102022

Web Style

P KP, S VV, Rajendra BN, A S, K TS, K P. Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?. https://www.njppp.com/?mno=117390 [Access: March 01, 2023]. doi:10.5455/njppp.2022.12.094592022014102022

AMA (American Medical Association) Style

P KP, S VV, Rajendra BN, A S, K TS, K P. Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?. Natl J Physiol Pharm Pharmacol. 2022; 12(11): 1875-1879. doi:10.5455/njppp.2022.12.094592022014102022

Vancouver/ICMJE Style

P KP, S VV, Rajendra BN, A S, K TS, K P. Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?. Natl J Physiol Pharm Pharmacol. (2022), [cited March 01, 2023]; 12(11): 1875-1879. doi:10.5455/njppp.2022.12.094592022014102022

Harvard Style

P, K. P., S, . V. V., Rajendra, . B. N., A, . S., K, . T. S. & K, . P. (2022) Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?. Natl J Physiol Pharm Pharmacol, 12 (11), 1875-1879. doi:10.5455/njppp.2022.12.094592022014102022

Turabian Style

P, Kalyani Praba, Vineetha V S, Bhavsar Nikhil Rajendra, Saravanan A, Thamarai Selvi K, and Prabhavathi K. 2022. Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?. National Journal of Physiology, Pharmacy and Pharmacology, 12 (11), 1875-1879. doi:10.5455/njppp.2022.12.094592022014102022

Chicago Style

P, Kalyani Praba, Vineetha V S, Bhavsar Nikhil Rajendra, Saravanan A, Thamarai Selvi K, and Prabhavathi K. "Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1875-1879. doi:10.5455/njppp.2022.12.094592022014102022

MLA (The Modern Language Association) Style

P, Kalyani Praba, Vineetha V S, Bhavsar Nikhil Rajendra, Saravanan A, Thamarai Selvi K, and Prabhavathi K. "Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?." National Journal of Physiology, Pharmacy and Pharmacology 12.11 (2022), 1875-1879. Print. doi:10.5455/njppp.2022.12.094592022014102022

APA (American Psychological Association) Style

P, K. P., S, . V. V., Rajendra, . B. N., A, . S., K, . T. S. & K, . P. (2022) Does periodontitis have synergistic effect in elevating serum creatinine level in type 2 diabetes mellitus?. National Journal of Physiology, Pharmacy and Pharmacology, 12 (11), 1875-1879. doi:10.5455/njppp.2022.12.094592022014102022

Author Login Reviewer Login About Publisher Editorial Policies Peer Review Policy Editorial & Peer Review Process Publication Ethics and Publication Malpractice Statement Conflict of Interest Policy Plagiarism Policy Protection of Research Participants (Statement On Human And Animal Rights)Corrections, Retractions & Expressions of Concern Self-Archiving Policies Statement of Informed Consent Advertising Policy Terms of Use License Information Copyright Information



Copyright © 2023 National Journal of Physiology, Pharmacy and Pharmacology All Rights Reserved. Subject to change without notice from or liability to National Journal of Physiology, Pharmacy and Pharmacology. For best results, please use Internet Explorer or Google Chrome	Contact Information Publisher publishernjppp@gmail.com Editorial query editornjppp1@gmail.com MOB - 8780040272

Contact Information

How to cite this article