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Original Research
Online Published: 07 Jan 2023
 


A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease

Mahesh Kumar, Bhagwan Singh Meena, Shubhangi Anand Kale.


Abstract
Background: One of the most prevalent chronic liver ailments is non-alcoholic fatty liver disease (NAFLD). The correction of numerous genes connected to various metabolic diseases depends heavily on Vitamin D.

Aims and Objectives: This investigation was intended to look at the relationships among those with NAFLD serum levels of Vitamin D, parathyroid hormone (PTH), insulin, and insulin resistance (IR).

Materials and Methods: Two hundred and fifty patients with NAFLD and 250 age-matched participants without NAFLD served as the study’s control group. Serum Vitamin D, PTH, insulin, and fasting blood glucose (FBG) levels were measured after 8–12 h of not eating or drinking. By controlling for the independent factors, the multivariate logistic regression analysis model was utilized to assess the relationship between Vitamin D, PTH, and IR in the occurrence of NAFLD.

Results: When compared to controls, patients with NAFLD had significantly lower serum Vitamin D levels and higher levels of PTH, insulin, and FBG (P = 0.001). Confounders had no impact on the association between NAFLD and the lower Vitamin D readings.

Conclusions: Our findings demonstrated that raised insulin and IR values and lower serum Vitamin D concentrations were each independently related with an increased risk of having NAFLD.

Key words: Vitamin D; Insulin Resistance; Parathyroid Hormone; NAFLD


 
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How to Cite this Article
Pubmed Style

Kumar M, Meena BS, Kale SA. A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease. Natl J Physiol Pharm Pharmacol. 2023; 13(2): 388-392. doi:10.5455/njppp.2023.13.12598202231122022

Web Style

Kumar M, Meena BS, Kale SA. A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease. https://www.njppp.com/?mno=101988 [Access: March 08, 2025]. doi:10.5455/njppp.2023.13.12598202231122022

AMA (American Medical Association) Style

Kumar M, Meena BS, Kale SA. A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease. Natl J Physiol Pharm Pharmacol. 2023; 13(2): 388-392. doi:10.5455/njppp.2023.13.12598202231122022


Vancouver/ICMJE Style

Kumar M, Meena BS, Kale SA. A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease. Natl J Physiol Pharm Pharmacol. (2023), [cited March 08, 2025]; 13(2): 388-392. doi:10.5455/njppp.2023.13.12598202231122022


Harvard Style

Kumar, M., Meena, . B. S. & Kale, . S. A. (2023) A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease. Natl J Physiol Pharm Pharmacol, 13 (2), 388-392. doi:10.5455/njppp.2023.13.12598202231122022


Turabian Style

Kumar, Mahesh, Bhagwan Singh Meena, and Shubhangi Anand Kale. 2023. A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease. National Journal of Physiology, Pharmacy and Pharmacology, 13 (2), 388-392. doi:10.5455/njppp.2023.13.12598202231122022


Chicago Style

Kumar, Mahesh, Bhagwan Singh Meena, and Shubhangi Anand Kale. "A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 388-392. doi:10.5455/njppp.2023.13.12598202231122022


MLA (The Modern Language Association) Style

Kumar, Mahesh, Bhagwan Singh Meena, and Shubhangi Anand Kale. "A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease." National Journal of Physiology, Pharmacy and Pharmacology 13.2 (2023), 388-392. Print. doi:10.5455/njppp.2023.13.12598202231122022


APA (American Psychological Association) Style

Kumar, M., Meena, . B. S. & Kale, . S. A. (2023) A study on parathyroid hormone and Vitamin D levels in patients with non-alcoholic fatty liver disease. National Journal of Physiology, Pharmacy and Pharmacology, 13 (2), 388-392. doi:10.5455/njppp.2023.13.12598202231122022


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