E-ISSN 2231-3206 | ISSN 2320-4672
 
2024, Vol: 14, Issue: 4
14 / 4Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Authorship Declaration

Original Research

Online Publishing Date:
16 / 02 / 2023

 


Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India

Rutvij H Hedamba, Kiran M Panchal, Hiren M Chawda.


Abstract
Background: According to other studies, second wave was different as compared to the first wave in clinical outcomes and laboratory parameters.

Aims and Objectives: We aimed to compare the clinicoepidemiological features and their effect on mortality in coronavirus disease-2019 (COVID-19) patients of first wave versus second wave.

Materials and Methods: We carried out cross-sectional, observational, and retrospective study among two groups of COVID-19 patients of first and second wave. Each group contains a 135 patients of COVID-19 admitted at our hospital. We analyzed the demographic profile, clinical features, comorbidities, and inflammatory markers.

Results: In our study, majority patients were male (67%). Majority number of the patients were between 18 and 60 years of age in both the groups. Presenting complaint of shortness of breath was significantly higher in second wave and sore throat was significantly higher in first wave. SpO2 on admission was significantly lower in second wave (93% vs. 98%). Median value of C-reactive protein (6.865 vs. 2.805), neutrophil-leucocyte ratio (4.647 vs. 2.917), and D-dimer (679.5 vs. 450) were significantly higher in second wave. Second wave had significantly higher mortality as compared to first wave (18.5% vs. 4.4%). However, level of D-dimer was found significantly higher in patients who died during first wave (6820 vs. 848). Higher mortality was seen in male patients of second wave.

Conclusion: Overall higher mortality was seen during the second wave which was supported by increased in the inflammatory markers. Delta variant, late admission, increased demand of oxygen support, and intensive care unit beds may have led to higher mortality.

Key words: Coronavirus Disease-2019; Clinicoepidemiological Features; First Wave; Second Wave; Mortality


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Rutvij H Hedamba
Articles by Kiran M Panchal
Articles by Hiren M Chawda
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Hedamba RH, Panchal KM, Chawda HM. Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India. Natl J Physiol Pharm Pharmacol. 2023; 13(4): 889-894. doi:10.5455/njppp.2023.13.01030202304022023

Web Style

Hedamba RH, Panchal KM, Chawda HM. Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India. https://www.njppp.com/?mno=140858 [Access: March 15, 2024]. doi:10.5455/njppp.2023.13.01030202304022023

AMA (American Medical Association) Style

Hedamba RH, Panchal KM, Chawda HM. Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India. Natl J Physiol Pharm Pharmacol. 2023; 13(4): 889-894. doi:10.5455/njppp.2023.13.01030202304022023


Vancouver/ICMJE Style

Hedamba RH, Panchal KM, Chawda HM. Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India. Natl J Physiol Pharm Pharmacol. (2023), [cited March 15, 2024]; 13(4): 889-894. doi:10.5455/njppp.2023.13.01030202304022023


Harvard Style

Hedamba, R. H., Panchal, . K. M. & Chawda, . H. M. (2023) Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India. Natl J Physiol Pharm Pharmacol, 13 (4), 889-894. doi:10.5455/njppp.2023.13.01030202304022023


Turabian Style

Hedamba, Rutvij H, Kiran M Panchal, and Hiren M Chawda. 2023. Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India. National Journal of Physiology, Pharmacy and Pharmacology, 13 (4), 889-894. doi:10.5455/njppp.2023.13.01030202304022023


Chicago Style

Hedamba, Rutvij H, Kiran M Panchal, and Hiren M Chawda. "Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 889-894. doi:10.5455/njppp.2023.13.01030202304022023


MLA (The Modern Language Association) Style

Hedamba, Rutvij H, Kiran M Panchal, and Hiren M Chawda. "Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India." National Journal of Physiology, Pharmacy and Pharmacology 13.4 (2023), 889-894. Print. doi:10.5455/njppp.2023.13.01030202304022023


APA (American Psychological Association) Style

Hedamba, R. H., Panchal, . K. M. & Chawda, . H. M. (2023) Comparative study of the clinicoepidemiological profile of COVID-19 patients of first wave and second wave admitted in a tertiary care teaching hospital in Nadiad, Gujarat, India. National Journal of Physiology, Pharmacy and Pharmacology, 13 (4), 889-894. doi:10.5455/njppp.2023.13.01030202304022023


Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Corrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About National Journal of Physiology, Pharmacy and Pharmacology

  National Journal of Physiology, Pharmacy and Pharmacology is a monthly peer reviewed journal.  The journal is having open access polic ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


Publisher

publishernjppp@gmail.com

 

Editorial query

editornjppp1@gmail.com

MOB - 8780040272