E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients

Mounika Vasa, Jabbala Kumar Raja, Madhukar Rao Polasani, Anurag Yadav.

Abstract
Background: In country like India, therapy with rosuvastatin recommended dose may cost between Rs. 400.00 and Rs. 800.00/month. The lower and middle income groups of Indian society are rapidly becoming major sufferers of cardiovascular disease, among all non-communicable diseases, the economic burden of rosuvastatin therapy may be substantial for this large section of population.

Aims and Objectives: The aim of the study was to study the cost-effectiveness of rosuvastatin on alternate day versus daily dosing regimen in hyperlipidemia patients.

Materials and Methods: The research was carried out at MNR Medical College and Hospital’s department of pharmacology in association with general medicine. According to the inclusion criteria, 50 patients aged 30–60 years of both sexes were included in this prospective open label trial. The research lasted 6 weeks. All the participants were included in study after obtaining the informed consent and approval of the Institutional Ethics Committee was obtained before enrolment of participants. All patient data were obtained using a pre-designed proforma and put into an excel spreadsheet.

Results: A total of 42 patients are included with 16 females (38%) and 26 men (62%). Cost of daily rosuvastatin for 6 weeks is Rs. 1087.80 (yearly daily dosing expenses 9453.50%) accounting for mean reduction of LDL-cholesterol (LDL-C) of 33.50% and for alternate day rosuvastatin for 6 weeks is 543.90% (yearly alternate day dosing expense 4713.80%) accounting for mean reduction of LDL-C of 31%.

Conclusion: Treatment with alternate day dose of rosuvastatin is comparably cost-effective when compared to currently practicing daily dose rosuvastatin therapy.

Key words: Rosuvastatin; Lipid; Pharmacoeconomics; Socio Economic Status; Coronary Vascular Disease


 
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How to Cite this Article
Pubmed Style

Vasa M, Raja JK, Polasani MR, Yadav A. Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 931-934. doi:10.5455/njppp.2023.13.06300202220092022


Web Style

Vasa M, Raja JK, Polasani MR, Yadav A. Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients. https://www.njppp.com/?mno=63464 [Access: September 03, 2023]. doi:10.5455/njppp.2023.13.06300202220092022


AMA (American Medical Association) Style

Vasa M, Raja JK, Polasani MR, Yadav A. Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 931-934. doi:10.5455/njppp.2023.13.06300202220092022



Vancouver/ICMJE Style

Vasa M, Raja JK, Polasani MR, Yadav A. Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients. Natl J Physiol Pharm Pharmacol. (2023), [cited September 03, 2023]; 13(5): 931-934. doi:10.5455/njppp.2023.13.06300202220092022



Harvard Style

Vasa, M., Raja, . J. K., Polasani, . M. R. & Yadav, . A. (2023) Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients. Natl J Physiol Pharm Pharmacol, 13 (5), 931-934. doi:10.5455/njppp.2023.13.06300202220092022



Turabian Style

Vasa, Mounika, Jabbala Kumar Raja, Madhukar Rao Polasani, and Anurag Yadav. 2023. Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 931-934. doi:10.5455/njppp.2023.13.06300202220092022



Chicago Style

Vasa, Mounika, Jabbala Kumar Raja, Madhukar Rao Polasani, and Anurag Yadav. "Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 931-934. doi:10.5455/njppp.2023.13.06300202220092022



MLA (The Modern Language Association) Style

Vasa, Mounika, Jabbala Kumar Raja, Madhukar Rao Polasani, and Anurag Yadav. "Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients." National Journal of Physiology, Pharmacy and Pharmacology 13.5 (2023), 931-934. Print. doi:10.5455/njppp.2023.13.06300202220092022



APA (American Psychological Association) Style

Vasa, M., Raja, . J. K., Polasani, . M. R. & Yadav, . A. (2023) Pharmacoeconomics study of rosuvastatin single daily dose versus alternate day dosing in hyperlipidemia patients. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 931-934. doi:10.5455/njppp.2023.13.06300202220092022