E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study

Kiran Bhave, Sweta Tondare, Prasad Pandit, Rachana Patankar.

Abstract
Background: Migraine is a debilitating neurological disorder. As a leading cause of disability worldwide, it affects health-related quality of life (HRQoL). There are limited studies assessing the prescription pattern and improvement in HRQoL post-treatment.

Aims and Objectives: This study aims to evaluate the drug use pattern and compare the effects of medications on HRQoL as per Migraine Disability Assessment Score (MIDAS).

Materials and Methods: A prospective observational cross-sectional study was conducted on migraine patients attending neurology OPD at a tertiary care hospital. One hundred and seven patients were recruited by periodic sampling over 6 months. Prescription indicators assessed were number of antimigraine drugs per prescription, frequency of prescribed drugs, prescriptions by generic name, etc. Data were analyzed using descriptive statistics. The HRQoL was assessed after 3 months of medications by telephonic questionnaire. The change was analyzed by Wilcoxon matched pair signed-rank test.

Results: Majority patients were in the third (40.2%) and fourth decade (32.7%) with a female preponderance (72.9%). Nonsteroidal anti-inflammatory drugs were commonly prescribed for aborting acute attacks with naproxen (24.1%) followed by diclofenac (2.71%). Prophylactically topiramate (27.51%), amitriptyline (18.6%), and propranolol (3.1%) were prescribed. About 36.43% of drugs were prescribed by generic names. Improvement in HRQoL was reflected by a significantly reduced MIDAS (13.95 ± 5.20 to 11.39 ± 5.07 [P < 0.05]).

Conclusion: In our study, there was low generic prescribing. Naproxen was most prescribed for acute migraine and topiramate for prophylaxis. The HRQoL significantly improved after 3 months of antimigraine medications causing lesser disease burden.

Key words: Headache; MIDAS; Prescription; HRQoL; Prophylaxis; Generic


 
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How to Cite this Article
Pubmed Style

Bhave K, Tondare S, Pandit P, Patankar R. Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study. Natl J Physiol Pharm Pharmacol. 2022; 12(11): 1939-1943. doi:10.5455/njppp.2022.12.0314520220002042022


Web Style

Bhave K, Tondare S, Pandit P, Patankar R. Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study. https://www.njppp.com/?mno=4707 [Access: November 24, 2022]. doi:10.5455/njppp.2022.12.0314520220002042022


AMA (American Medical Association) Style

Bhave K, Tondare S, Pandit P, Patankar R. Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study. Natl J Physiol Pharm Pharmacol. 2022; 12(11): 1939-1943. doi:10.5455/njppp.2022.12.0314520220002042022



Vancouver/ICMJE Style

Bhave K, Tondare S, Pandit P, Patankar R. Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study. Natl J Physiol Pharm Pharmacol. (2022), [cited November 24, 2022]; 12(11): 1939-1943. doi:10.5455/njppp.2022.12.0314520220002042022



Harvard Style

Bhave, K., Tondare, . S., Pandit, . P. & Patankar, . R. (2022) Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study. Natl J Physiol Pharm Pharmacol, 12 (11), 1939-1943. doi:10.5455/njppp.2022.12.0314520220002042022



Turabian Style

Bhave, Kiran, Sweta Tondare, Prasad Pandit, and Rachana Patankar. 2022. Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (11), 1939-1943. doi:10.5455/njppp.2022.12.0314520220002042022



Chicago Style

Bhave, Kiran, Sweta Tondare, Prasad Pandit, and Rachana Patankar. "Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1939-1943. doi:10.5455/njppp.2022.12.0314520220002042022



MLA (The Modern Language Association) Style

Bhave, Kiran, Sweta Tondare, Prasad Pandit, and Rachana Patankar. "Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study." National Journal of Physiology, Pharmacy and Pharmacology 12.11 (2022), 1939-1943. Print. doi:10.5455/njppp.2022.12.0314520220002042022



APA (American Psychological Association) Style

Bhave, K., Tondare, . S., Pandit, . P. & Patankar, . R. (2022) Drug use pattern and quality of life in patients with migraine at a tertiary care hospital in India: An observational study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (11), 1939-1943. doi:10.5455/njppp.2022.12.0314520220002042022