Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal

Phalguni Chakrabarti; Aparajita Samaddar; Arup Chakraborty; Debasis Mukhopadhyay; Swapan Pathak

doi:10.5455/njppp.2022.12.12441202113122021

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Online Published: 19 Dec 2021

Natl J Physiol Pharm Pharmacol. 2022; 12(1): 97-101

doi: 10.5455/njppp.2022.12.12441202113122021

Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal

Phalguni Chakrabarti, Aparajita Samaddar, Arup Chakraborty, Debasis Mukhopadhyay, Swapan Pathak.

Cited By:4

Abstract
Background: Dyslipidemia is one of the common conditions associated with poor glycemic control in Type 2 diabetes mellitus (T2DM) patients. It is associated with an increased risk of cardiovascular disease which is the leading cause of death in these patients. Glycated Hemoglobin (HbA1c) is the gold standard test for monitoring glycemic control. Thus, the level of HbA1c could potentially be utilized as a possible biomarker for predicting the risk of dyslipidemia. However, there is a discrepancy in the data available till now regarding the relationship between HbA1c and the lipid profile. Hence, it requires further studies.

Aim and Objectives: The present study was conducted to assess the role of glycemic control (as indicated by HbA1c level in blood) on lipid profile of patients with T2DM.

Materials and Methods: This was an analytical cross-sectional study done over a period of 5 months. Total 165 participants were randomly selected from out patient department OPD of which 138 were diagnosed cases of T2DM and 27 were age and sex-matched non-diabetic healthy individuals. Patients of T2DM were sub grouped based on American Diabetic Association Criteria (2013) as having either controlled diabetes with HbA1c ≤7% or uncontrolled diabetes with HbA1c >7%. Blood samples collected from all the participants were analyzed for HbA1c and lipid profile using standard methods. The collected data were analyzed with Statistical Package for the Social Sciences software using appropriate statistical method.

Results: In the present study, we found a significant positive correlation between HbA1c and total cholesterol, Triglyceride, Low-density lipoproteins, and very low-density lipoproteins (P < 0.01) though high-density lipoprotein was not significantly correlated with HbA1c level.

Conclusion: We concluded that apart from a reliable index of glycemic control, HbA1c can also be used as a predictor of dyslipidemia in T2DM patients, and thus regular monitoring of it can help us to reduce the mortality of these patients.

Key words: Glycated Haemoglobin; Lipid Profile; Type 2 Diabetes Mellitus

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Pubmed Style

Chakrabarti P, Samaddar A, Chakraborty A, Mukhopadhyay D, Pathak S. Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal. Natl J Physiol Pharm Pharmacol. 2022; 12(1): 97-101. doi:10.5455/njppp.2022.12.12441202113122021

Web Style

Chakrabarti P, Samaddar A, Chakraborty A, Mukhopadhyay D, Pathak S. Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal. https://www.njppp.com/?mno=40230 [Access: November 01, 2024]. doi:10.5455/njppp.2022.12.12441202113122021

AMA (American Medical Association) Style

Chakrabarti P, Samaddar A, Chakraborty A, Mukhopadhyay D, Pathak S. Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal. Natl J Physiol Pharm Pharmacol. 2022; 12(1): 97-101. doi:10.5455/njppp.2022.12.12441202113122021

Vancouver/ICMJE Style

Chakrabarti P, Samaddar A, Chakraborty A, Mukhopadhyay D, Pathak S. Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal. Natl J Physiol Pharm Pharmacol. (2022), [cited November 01, 2024]; 12(1): 97-101. doi:10.5455/njppp.2022.12.12441202113122021

Harvard Style

Chakrabarti, P., Samaddar, . A., Chakraborty, . A., Mukhopadhyay, . D. & Pathak, . S. (2022) Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal. Natl J Physiol Pharm Pharmacol, 12 (1), 97-101. doi:10.5455/njppp.2022.12.12441202113122021

Turabian Style

Chakrabarti, Phalguni, Aparajita Samaddar, Arup Chakraborty, Debasis Mukhopadhyay, and Swapan Pathak. 2022. Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal. National Journal of Physiology, Pharmacy and Pharmacology, 12 (1), 97-101. doi:10.5455/njppp.2022.12.12441202113122021

Chicago Style

Chakrabarti, Phalguni, Aparajita Samaddar, Arup Chakraborty, Debasis Mukhopadhyay, and Swapan Pathak. "Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 97-101. doi:10.5455/njppp.2022.12.12441202113122021

MLA (The Modern Language Association) Style

Chakrabarti, Phalguni, Aparajita Samaddar, Arup Chakraborty, Debasis Mukhopadhyay, and Swapan Pathak. "Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal." National Journal of Physiology, Pharmacy and Pharmacology 12.1 (2022), 97-101. Print. doi:10.5455/njppp.2022.12.12441202113122021

APA (American Psychological Association) Style

Chakrabarti, P., Samaddar, . A., Chakraborty, . A., Mukhopadhyay, . D. & Pathak, . S. (2022) Role of glycemic control on lipid profile in patients with type 2 diabetes mellitus-a cross-sectional study in tertiary care hospital of West Bengal. National Journal of Physiology, Pharmacy and Pharmacology, 12 (1), 97-101. doi:10.5455/njppp.2022.12.12441202113122021

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