Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study

C L Meena; Harsa R; V K Meena; Anju Bharti; Rajani Nawal; L P Meena; Nilesh Kumar; RN Meena

doi:10.5455/njppp.2013.3.87-91

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Online Published: 08 Jan 2013

Natl J Physiol Pharm Pharmacol. 2013; 3(1): 87-91

doi: 10.5455/njppp.2013.3.87-91

Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, Rn Meena.

Cited By:9

Abstract
Background : The relationship between uric acid and microalbuminuria in healthy adults without other cardiovascular risk factors may help to clarify the role of uric acid in cardiovascular disease.
Objectives: To study and compare the association of serum uric acid levels with microalbuminuria in normotensive and prehypertensive subjects without a history of cardiovascular disease or renal dysfunction.
Material and Methods :350 subjects were included in study. All the routine investigations along with serum uric acid and urinary albumin were conducted . Microalbuminuria was detected by immunoprecipitation in a random urine sample. Serum uric acid level was estimated by Spectrophotometry.
Results:The overall prevalence of prehypertension was 38.06% (Males,39.10% and females, 35.56%). The total prevalence of microalbuminuria was 11.61% ( 9.9% of normotensives and 14.4% of prehypertensives ).Hyperuricemia was seen in 10.32% of the total study population.Among normotensives, 9% of males and 8.6% of females and in prehypertensive subjects, 14% of males & 9.4% of females had hyperuricemia. Among the prehypertensives, those with microalbuminuria had a significantly higher (p<0.001) serum uric acid level (7.024 + 1.023 mg/dl) as compared to those without microalbuminuria (5.089 +0.965mg/dl).
Conclusion:This study demonstrates a strong independent association between uric acid level and microalbuminuria in prehypertensive subjects without a history of cardiovascular disease, diabetes decreased renal function.

Key words: Microalbuminuria, Uric acid ,prehypertension, India.

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Pubmed Style

Meena CL, R H, Meena VK, Bharti A, Nawal R, Meena LP, Kumar N, Meena R. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol. 2013; 3(1): 87-91. doi:10.5455/njppp.2013.3.87-91

Web Style

Meena CL, R H, Meena VK, Bharti A, Nawal R, Meena LP, Kumar N, Meena R. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. https://www.njppp.com/?mno=28885 [Access: May 05, 2025]. doi:10.5455/njppp.2013.3.87-91

AMA (American Medical Association) Style

Meena CL, R H, Meena VK, Bharti A, Nawal R, Meena LP, Kumar N, Meena R. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol. 2013; 3(1): 87-91. doi:10.5455/njppp.2013.3.87-91

Vancouver/ICMJE Style

Meena CL, R H, Meena VK, Bharti A, Nawal R, Meena LP, Kumar N, Meena R. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol. (2013), [cited May 05, 2025]; 3(1): 87-91. doi:10.5455/njppp.2013.3.87-91

Harvard Style

Meena, C. L., R, . H., Meena, . V. K., Bharti, . A., Nawal, . R., Meena, . L. P., Kumar, . N. & Meena, . R. (2013) Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol, 3 (1), 87-91. doi:10.5455/njppp.2013.3.87-91

Turabian Style

Meena, C L, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, and Rn Meena. 2013. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 3 (1), 87-91. doi:10.5455/njppp.2013.3.87-91

Chicago Style

Meena, C L, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, and Rn Meena. "Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study." National Journal of Physiology, Pharmacy and Pharmacology 3 (2013), 87-91. doi:10.5455/njppp.2013.3.87-91

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Meena, C. L., R, . H., Meena, . V. K., Bharti, . A., Nawal, . R., Meena, . L. P., Kumar, . N. & Meena, . R. (2013) Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 3 (1), 87-91. doi:10.5455/njppp.2013.3.87-91

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