Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study

Padmaja Rajey Desai; Sunita Milind Tiwale; Pandian Murugesan Devar; Rajey M Desai

doi:10.5455/njppp.2017.7.0413325042017

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Online Published: 20 May 2017

Natl J Physiol Pharm Pharmacol. 2017; 7(9): 957-962

doi: 10.5455/njppp.2017.7.0413325042017

Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study

Padmaja Rajey Desai, Sunita Milind Tiwale, Pandian Murugesan Devar, Rajey M Desai.

Abstract
Background: Doppler velocimetry studies of placental and fetal circulation can provide important information regarding fetal well-being providing an opportunity to improve fetal outcome.

Aims and Objective: The aim of this study to evaluate the role of color Doppler velocimetry of the fetal middle cerebral artery (MCA) velocity waveforms, systolic/diastolic ratio (S/D), pulsatility index (PI), and resistance index (RI) in intrauterine growth restriction (IUGR) pregnancies in II and III trimesters.

Materials and Methods: This was a cross-sectional study. The control and study groups were studied in II and III trimesters. They were first subjected to ultrasonography biometry and then to MCA Doppler sonography. The statistical analysis was performed by unpaired and paired t-test.

Results: In both control and study groups, the values of S/D ratio, PI, and RI in MCA decline during II to III trimester. The values were lower in the study group as compared to the control group. Thus that the present study predicts were; (a) lower PI values were suggestive of fetal hypoxia, (b) The lower values are due to vasodilatation due to hypoxia to supply more blood to the brain to protect it from the damaging effects of hypoxia. Thus, the brain is spared from damage.

Conclusion: Doppler can be considered as one of the important non-invasive techniques to assess the fetomaternal and uteroplacental circulations. The MCA indices were valuable for predicting the outcome of IUGR pregnancies.

Key words: Fetal Growth Restriction; Middle Cerebral Artery Doppler Sonography; Perinatal Outcome

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Pubmed Style

Desai PR, Tiwale SM, Devar PM, Desai RM. Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 957-962. doi:10.5455/njppp.2017.7.0413325042017

Web Style

Desai PR, Tiwale SM, Devar PM, Desai RM. Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study. https://www.njppp.com/?mno=264966 [Access: November 01, 2025]. doi:10.5455/njppp.2017.7.0413325042017

AMA (American Medical Association) Style

Desai PR, Tiwale SM, Devar PM, Desai RM. Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 957-962. doi:10.5455/njppp.2017.7.0413325042017

Vancouver/ICMJE Style

Desai PR, Tiwale SM, Devar PM, Desai RM. Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study. Natl J Physiol Pharm Pharmacol. (2017), [cited November 01, 2025]; 7(9): 957-962. doi:10.5455/njppp.2017.7.0413325042017

Harvard Style

Desai, P. R., Tiwale, . S. M., Devar, . P. M. & Desai, . R. M. (2017) Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study. Natl J Physiol Pharm Pharmacol, 7 (9), 957-962. doi:10.5455/njppp.2017.7.0413325042017

Turabian Style

Desai, Padmaja Rajey, Sunita Milind Tiwale, Pandian Murugesan Devar, and Rajey M Desai. 2017. Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 957-962. doi:10.5455/njppp.2017.7.0413325042017

Chicago Style

Desai, Padmaja Rajey, Sunita Milind Tiwale, Pandian Murugesan Devar, and Rajey M Desai. "Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 957-962. doi:10.5455/njppp.2017.7.0413325042017

MLA (The Modern Language Association) Style

Desai, Padmaja Rajey, Sunita Milind Tiwale, Pandian Murugesan Devar, and Rajey M Desai. "Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 7.9 (2017), 957-962. Print. doi:10.5455/njppp.2017.7.0413325042017

APA (American Psychological Association) Style

Desai, P. R., Tiwale, . S. M., Devar, . P. M. & Desai, . R. M. (2017) Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 957-962. doi:10.5455/njppp.2017.7.0413325042017

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