Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis

Atanu Roy; Sanjeev K. Singh

doi:10.5455/njppp.2017.7.0410120042017

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Online Published: 18 May 2017

Natl J Physiol Pharm Pharmacol. 2017; 7(9): 924-928

doi: 10.5455/njppp.2017.7.0410120042017

Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis

Atanu Roy, Sanjeev K. Singh.

Cited By:2

Abstract
Background: Ankylosing spondylitis (AS) is an autoimmune disease which leads to the involvement of skeletal, cardiac, nervous tissues, and other systemic diseases.

Aims and Objectives: This study was conducted to assess the cardiac sympathovagal responses in the AS patients using Valsalva maneuver (VM) and tilt-table test (TTT).

Materials and Methods: A total of 30 AS patients having Bath AS Disease Activity Index of ≥4 were included in this study. The same numbers of age- and sex-matched controls were also selected. The blood pressure (BP) and electrocardiogram were recorded during VM and TTT. The Valsalva ratio and 30:15 ratio were calculated.

Results: During VM, there is a statistically significant decrease in the Valsalva ratio in the cases (P < 0.05). After TTT, there is a significant decrease in 30:15 ratio and significant increase in systolic BP (SBP) in the cases (P < 0.05).

Conclusion: The Valsalva ratio in the cases is decreased indicating the parasympathetic loss which is further supported by the decrease in 30:15 ratio observed after TTT. The increase in SBP in cases also supports the shifting of sympathovagal balance toward the sympathetic side.

Key words: Valsalva Maneuver; Tilt-Table Test; Ankylosing Spondylitis; Autonomic Nervous System

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Pubmed Style

Roy A, Singh SK. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 924-928. doi:10.5455/njppp.2017.7.0410120042017

Web Style

Roy A, Singh SK. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. https://www.njppp.com/?mno=263111 [Access: November 02, 2025]. doi:10.5455/njppp.2017.7.0410120042017

AMA (American Medical Association) Style

Roy A, Singh SK. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 924-928. doi:10.5455/njppp.2017.7.0410120042017

Vancouver/ICMJE Style

Roy A, Singh SK. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol. (2017), [cited November 02, 2025]; 7(9): 924-928. doi:10.5455/njppp.2017.7.0410120042017

Harvard Style

Roy, A. & Singh, . S. K. (2017) Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol, 7 (9), 924-928. doi:10.5455/njppp.2017.7.0410120042017

Turabian Style

Roy, Atanu, and Sanjeev K. Singh. 2017. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 924-928. doi:10.5455/njppp.2017.7.0410120042017

Chicago Style

Roy, Atanu, and Sanjeev K. Singh. "Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 924-928. doi:10.5455/njppp.2017.7.0410120042017

MLA (The Modern Language Association) Style

Roy, Atanu, and Sanjeev K. Singh. "Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis." National Journal of Physiology, Pharmacy and Pharmacology 7.9 (2017), 924-928. Print. doi:10.5455/njppp.2017.7.0410120042017

APA (American Psychological Association) Style

Roy, A. & Singh, . S. K. (2017) Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 924-928. doi:10.5455/njppp.2017.7.0410120042017

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