Evaluation of vascular function in depigmented black women: Comparative study

Arame Mbengue; Mor Diaw; Gerard Akpo; Hamidou Deme; Valentin Ouedraogo; Abdou K Sow; Oumar Diop; Arnaud Jean Florent Tiendrebeogo; Fatoumata Ba; Mamadou Mbdji; Aissatou Seck; Saliamata Diagne Houndjo; Maimouna Toure; Mame Saloum Coly; Fatou Bintou Sarr; Abdoulaye Ba; Abdoulaye Samb

doi:10.5455/njppp.2017.7.1233202012017

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Original Research
Online Published: 11 Jan 2017

Natl J Physiol Pharm Pharmacol. 2017; 7(4): 420-424

doi: 10.5455/njppp.2017.7.1233202012017

Evaluation of vascular function in depigmented black women: Comparative study

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb.

Cited By:3

Abstract
Background: Prolonged application of skin depigmenting substances could expose human organism to serious general complications such as hypertension or diabetes. Artificial depigmentation (AD) is a widespread practice within Sub-Saharan Africa subjects. AD is based on the use of dermocorticoides which could lead to vascular complications.

Aims and Objectives: Our aim was to evaluate the vascular function in depigmented Senegalese women.

Materials and Methods: Thirty six depigmented (depigmented group) and 36 undepigmented black women (control group) participated in the study. They were aged 33.10 ± 7 years and 30.22 ± 6 years, respectively. Brachial artery flow mediated dilation (FMD) was measured in two groups. Biochemical and cardiovascular profiles of our study population were evaluated. The duration of depigmenting products exposure was evaluated in depigmented subjects.

Results: Our study showed an abnormal kinetic of FMD in depigmented group compared to control group. Mean arterial pressure was 95.9 ± 8.8 mmHg in depigmented subjects and 89.6 ± 6.2 mmHg for control subjects and a significant difference was observed (P = 0.002) while triglycerides was significantly different (P = 0.01) between the two groups (0.8 ± 0.3 and 0.6 ± 0.2 g/L, respectively). FMD was significantly and positively correlated with exposure time (r = 0.25; P = 0.029).

Conclusion: Prolonged percutaneous application of depigmentation products could alter metabolic and vascular functions, and consequently install cardiovascular risks. Thus, we recommended ways to prevent of AD in the African population.

Key words: Artificial Depigmentation; Black Population; Vascular Function

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How to Cite this Article

Pubmed Style

Mbengue A, Diaw M, Akpo G, Deme H, Ouedraogo V, Sow AK, Diop O, Tiendrebeogo AJF, Ba F, Mbdji M, Seck A, Houndjo SD, Toure M, Coly MS, Sarr FB, Ba A, Samb A. Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol. 2017; 7(4): 420-424.

doi:10.5455/njppp.2017.7.1233202012017

Web Style

Mbengue A, Diaw M, Akpo G, Deme H, Ouedraogo V, Sow AK, Diop O, Tiendrebeogo AJF, Ba F, Mbdji M, Seck A, Houndjo SD, Toure M, Coly MS, Sarr FB, Ba A, Samb A. Evaluation of vascular function in depigmented black women: Comparative study. https://www.njppp.com/?mno=251168 [Access: June 27, 2026].

doi:10.5455/njppp.2017.7.1233202012017

AMA (American Medical Association) Style

Mbengue A, Diaw M, Akpo G, Deme H, Ouedraogo V, Sow AK, Diop O, Tiendrebeogo AJF, Ba F, Mbdji M, Seck A, Houndjo SD, Toure M, Coly MS, Sarr FB, Ba A, Samb A. Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol. 2017; 7(4): 420-424.

doi:10.5455/njppp.2017.7.1233202012017

Vancouver/ICMJE Style

Mbengue A, Diaw M, Akpo G, Deme H, Ouedraogo V, Sow AK, Diop O, Tiendrebeogo AJF, Ba F, Mbdji M, Seck A, Houndjo SD, Toure M, Coly MS, Sarr FB, Ba A, Samb A. Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol. (2017), [cited June 27, 2026]; 7(4): 420-424.

doi:10.5455/njppp.2017.7.1233202012017

Harvard Style

Mbengue, A., Diaw, . M., Akpo, . G., Deme, . H., Ouedraogo, . V., Sow, . A. K., Diop, . O., Tiendrebeogo, . A. J. F., Ba, . F., Mbdji, . M., Seck, . A., Houndjo, . S. D., Toure, . M., Coly, . M. S., Sarr, . F. B., Ba, . A. & Samb, . A. (2017) Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol, 7 (4), 420-424.

doi:10.5455/njppp.2017.7.1233202012017

Turabian Style

Mbengue, Arame, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, and Abdoulaye Samb. 2017. Evaluation of vascular function in depigmented black women: Comparative study. National Journal of Physiology, Pharmacy and Pharmacology, 7 (4), 420-424.

doi:10.5455/njppp.2017.7.1233202012017

Chicago Style

Mbengue, Arame, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, and Abdoulaye Samb. "Evaluation of vascular function in depigmented black women: Comparative study." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 420-424.

doi:10.5455/njppp.2017.7.1233202012017

MLA (The Modern Language Association) Style

Mbengue, Arame, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, and Abdoulaye Samb. "Evaluation of vascular function in depigmented black women: Comparative study." National Journal of Physiology, Pharmacy and Pharmacology 7.4 (2017), 420-424. Print.

doi:10.5455/njppp.2017.7.1233202012017

APA (American Psychological Association) Style

doi:10.5455/njppp.2017.7.1233202012017

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