Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions

Asankul A. Kucherbaev; Jury V. Borjakin; Kubat S. Ibraimov; Aigul B. Cherikchieva

doi:10.5455/njppp.2016.6.0512610062016

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Original Research
Online Published: 31 Aug 2016

Natl J Physiol Pharm Pharmacol. 2016; 6(5): 445-448

doi: 10.5455/njppp.2016.6.0512610062016

Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva.

Abstract
Background: The paper presents data on the structure and the function of erythrocyte membranes in moderate degree iron-deficiency anemia (IDA) in early-age children living in mountain conditions.

Aim and Objectives: Explore pathogenic mechanisms for membrane destructive disorders in IDA in the early-age children living in the high-mountain area and develop a program for diagnostics and reasonable kinds of etiopathogenetic therapy.

Materials and Methods: Research was made in high-mountain regions of the Kyrgyz Republic. A clinical supervision was made in dynamics with a focus on a structure of peripheral blood, maintained phospholipids fractions detected in erythrocytes membranes with a method of thin-layer chromatography on Silufol plates and with a quantitative definition of phosphorus by Barlets method.

Result: In IDA in children in the mountain area, there is a disorder in phospholipids between blood plasma and red blood cells with an accumulation of the lizoform.

Conclusion: The paper presents the findings that relate to pathogenic mechanisms for disorders in the phospholipid composition of erythrocytes membranes in moderate degree IDA among 170 early-age children living in the high mountains zone in the Kyrgyz Republic. The paper also includes the indicators and presents results saying of a positive dynamic in specific membrane phospholipids of erythrocyte disorders liquidation in the treatment with a preparation of iron sulfate with folic acid.

Key words: Early-age Children; Erythrocytes; Iron-deficiency Anemia; High Mountains

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How to Cite this Article

Pubmed Style

Kucherbaev AA, Borjakin JV, Ibraimov KS, Cherikchieva AB. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 445-448. doi:10.5455/njppp.2016.6.0512610062016

Web Style

Kucherbaev AA, Borjakin JV, Ibraimov KS, Cherikchieva AB. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. https://www.njppp.com/?mno=228174 [Access: November 02, 2025]. doi:10.5455/njppp.2016.6.0512610062016

AMA (American Medical Association) Style

Kucherbaev AA, Borjakin JV, Ibraimov KS, Cherikchieva AB. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 445-448. doi:10.5455/njppp.2016.6.0512610062016

Vancouver/ICMJE Style

Kucherbaev AA, Borjakin JV, Ibraimov KS, Cherikchieva AB. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol. (2016), [cited November 02, 2025]; 6(5): 445-448. doi:10.5455/njppp.2016.6.0512610062016

Harvard Style

Kucherbaev, A. A., Borjakin, . J. V., Ibraimov, . K. S. & Cherikchieva, . A. B. (2016) Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol, 6 (5), 445-448. doi:10.5455/njppp.2016.6.0512610062016

Turabian Style

Kucherbaev, Asankul A., Jury V. Borjakin, Kubat S. Ibraimov, and Aigul B. Cherikchieva. 2016. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 445-448. doi:10.5455/njppp.2016.6.0512610062016

Chicago Style

Kucherbaev, Asankul A., Jury V. Borjakin, Kubat S. Ibraimov, and Aigul B. Cherikchieva. "Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 445-448. doi:10.5455/njppp.2016.6.0512610062016

MLA (The Modern Language Association) Style

Kucherbaev, Asankul A., Jury V. Borjakin, Kubat S. Ibraimov, and Aigul B. Cherikchieva. "Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions." National Journal of Physiology, Pharmacy and Pharmacology 6.5 (2016), 445-448. Print. doi:10.5455/njppp.2016.6.0512610062016

APA (American Psychological Association) Style

Kucherbaev, A. A., Borjakin, . J. V., Ibraimov, . K. S. & Cherikchieva, . A. B. (2016) Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 445-448. doi:10.5455/njppp.2016.6.0512610062016

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