E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research
Online Published: 02 Jan 2025


A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India

Seema Sankeshwari, Ambuja Sambrani, Mahajabeen Madarkar, Sangeeta Dhulappanavar Ravi, Devarapalli Srikanth.


Abstract
Background:
Most airway obstruction i.e. about 89% occurs during general anesthesia and 70% involve upper airway. Henceforth, choosing an appropriate choice of sedative to decrease the respiratory morbidity during post anesthetic period is utmost important.

Aim:
To analyze the peak expiratory flow rate in propofol & midazolam induced post anesthetic patients separately and compare.

Methods:
This is a comparative study of measuring PEFR in post anesthetic patients between propofol induced and midazolam induced patients. A sample size of 30 were taken, among which 15 were propofol induced and 15 were midazolam induced subjects.

Results:
Mean values of Avg PEFR readings of propofol and midazolam showed a p-value of 0.0001 which is statistically significant. Mean PEFR values of Males and Females in Propofol induction showed a p-value of 0.0007 which is statistically significant. Mean PEFR values of Males and Females in Midazolam induction showed a p-value of 0.0092 which is statistically significant.

Conclusion:
Midazolam significantly depresses respiratory system more than propofol. And females irrespective of the anesthetic drug used for induction showed low PEFR values as compared to males.

Key words: Propofol, Midazolam, PEFR in Anesthesia, Anesthesia in respiratory illness, Comparison between midazolam and propofol in sedation


 
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How to Cite this Article
Pubmed Style

Sankeshwari S, Sambrani A, Madarkar M, Ravi SD, Srikanth D. A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India. Natl J Physiol Pharm Pharmacol. 2025; 15(1): 58-62. doi:10.5455/NJPPP.2025.v15.i1.10


Web Style

Sankeshwari S, Sambrani A, Madarkar M, Ravi SD, Srikanth D. A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India. https://www.njppp.com/?mno=225220 [Access: February 12, 2025]. doi:10.5455/NJPPP.2025.v15.i1.10


AMA (American Medical Association) Style

Sankeshwari S, Sambrani A, Madarkar M, Ravi SD, Srikanth D. A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India. Natl J Physiol Pharm Pharmacol. 2025; 15(1): 58-62. doi:10.5455/NJPPP.2025.v15.i1.10



Vancouver/ICMJE Style

Sankeshwari S, Sambrani A, Madarkar M, Ravi SD, Srikanth D. A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India. Natl J Physiol Pharm Pharmacol. (2025), [cited February 12, 2025]; 15(1): 58-62. doi:10.5455/NJPPP.2025.v15.i1.10



Harvard Style

Sankeshwari, S., Sambrani, . A., Madarkar, . M., Ravi, . S. D. & Srikanth, . D. (2025) A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India. Natl J Physiol Pharm Pharmacol, 15 (1), 58-62. doi:10.5455/NJPPP.2025.v15.i1.10



Turabian Style

Sankeshwari, Seema, Ambuja Sambrani, Mahajabeen Madarkar, Sangeeta Dhulappanavar Ravi, and Devarapalli Srikanth. 2025. A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India. National Journal of Physiology, Pharmacy and Pharmacology, 15 (1), 58-62. doi:10.5455/NJPPP.2025.v15.i1.10



Chicago Style

Sankeshwari, Seema, Ambuja Sambrani, Mahajabeen Madarkar, Sangeeta Dhulappanavar Ravi, and Devarapalli Srikanth. "A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India." National Journal of Physiology, Pharmacy and Pharmacology 15 (2025), 58-62. doi:10.5455/NJPPP.2025.v15.i1.10



MLA (The Modern Language Association) Style

Sankeshwari, Seema, Ambuja Sambrani, Mahajabeen Madarkar, Sangeeta Dhulappanavar Ravi, and Devarapalli Srikanth. "A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India." National Journal of Physiology, Pharmacy and Pharmacology 15.1 (2025), 58-62. Print. doi:10.5455/NJPPP.2025.v15.i1.10



APA (American Psychological Association) Style

Sankeshwari, S., Sambrani, . A., Madarkar, . M., Ravi, . S. D. & Srikanth, . D. (2025) A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India. National Journal of Physiology, Pharmacy and Pharmacology, 15 (1), 58-62. doi:10.5455/NJPPP.2025.v15.i1.10