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Original Research
Online Published: 22 Jun 2024
 


Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections

Favas K, Muhammed Aslam Tk, Noushadali Ak, Santhosh Jose.


Abstract
Background: Urinary tract infections (UTIs) in children are among the most frequent bacterial infections they may suffer, causing a considerable degree of morbidity. The emergence of uropathogens resistant to antimicrobial agents is making treatment and management more difficult.

Aims and Objectives: The aims and objectives of study are to evaluate the patterns of antimicrobial susceptibilities and resistance among common uropathogens in pediatric UTIs.

Materials and Methods: This is one-year cross-sectional study at MES Medical College, Perinthalmanna, on patients undergoing laparoscopic cholecystectomy for symptomatic gallstones. Fifty-four children had a culture-confirmed UTI; their urine samples were studied. All pathogens were tested for antibiotic susceptibility using the Kirby–Bauer disk diffusion method.

Results: Escherichia coli was the most common pathogen isolated, followed by Klebsiella pneumoniae and Pseudomonas aeruginosa. There was a low sensitivity for cephalexin and cefepime (12.03–26.75%), whereas piperacillin-tazobactam (100%) and amikacin had high sensitivity (88.89%).

Conclusion: The present study showed high antimicrobial resistance among common uropathogens causing pediatric UTIs. Optimal treatment aims to reduce the spread of resistant strains, necessitating continued monitoring of resistance patterns and the conservative use of antibiotics.

Key words: Pediatric Urinary Tract Infection; Antimicrobial Resistance; Uropathogens; Escherichia coli; Antibiotic Susceptibility


 
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How to Cite this Article
Pubmed Style

K F, Tk MA, Ak N, Jose S. Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections. Natl J Physiol Pharm Pharmacol. 2024; 14(8): 1686-1690. doi:10.5455/njppp.2024.14.06238202411062024

Web Style

K F, Tk MA, Ak N, Jose S. Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections. https://www.njppp.com/?mno=204180 [Access: April 18, 2025]. doi:10.5455/njppp.2024.14.06238202411062024

AMA (American Medical Association) Style

K F, Tk MA, Ak N, Jose S. Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections. Natl J Physiol Pharm Pharmacol. 2024; 14(8): 1686-1690. doi:10.5455/njppp.2024.14.06238202411062024


Vancouver/ICMJE Style

K F, Tk MA, Ak N, Jose S. Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections. Natl J Physiol Pharm Pharmacol. (2024), [cited April 18, 2025]; 14(8): 1686-1690. doi:10.5455/njppp.2024.14.06238202411062024


Harvard Style

K, F., Tk, . M. A., Ak, . N. & Jose, . S. (2024) Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections. Natl J Physiol Pharm Pharmacol, 14 (8), 1686-1690. doi:10.5455/njppp.2024.14.06238202411062024


Turabian Style

K, Favas, Muhammed Aslam Tk, Noushadali Ak, and Santhosh Jose. 2024. Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections. National Journal of Physiology, Pharmacy and Pharmacology, 14 (8), 1686-1690. doi:10.5455/njppp.2024.14.06238202411062024


Chicago Style

K, Favas, Muhammed Aslam Tk, Noushadali Ak, and Santhosh Jose. "Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 1686-1690. doi:10.5455/njppp.2024.14.06238202411062024


MLA (The Modern Language Association) Style

K, Favas, Muhammed Aslam Tk, Noushadali Ak, and Santhosh Jose. "Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections." National Journal of Physiology, Pharmacy and Pharmacology 14.8 (2024), 1686-1690. Print. doi:10.5455/njppp.2024.14.06238202411062024


APA (American Psychological Association) Style

K, F., Tk, . M. A., Ak, . N. & Jose, . S. (2024) Antimicrobial susceptibility and resistance patterns in pediatric urinary tract infections. National Journal of Physiology, Pharmacy and Pharmacology, 14 (8), 1686-1690. doi:10.5455/njppp.2024.14.06238202411062024


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