E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research
Online Published: 31 May 2024
 


A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study

Anitha Elango, Neevedha Kannan, Isswariya Anandan, Surapaneni Krishna Mohan.


Abstract
Background: COVID-19 was a dreadful disease that turned into a pandemic, which made drug therapy a challenging task. With the advancement of medical science, the treatment of diseases has become much more sophisticated and with the advent of the vaccination system, the prevention of dreadful diseases that affect vast human communities can be effective is possible.

Aims and Objectives: This work was initiated to understand the safety of Covishield™ by following the patients for any possible side effects and adverse effects after 1st and 2nd doses of vaccination.

Materials and Methods: This retrospective cohort study was conducted in Panimalar Medical College Hospital and Research Institute, Chennai, India, on participants who got vaccinated with Covishield™ and reported the adverse effects that were noticed after 14 days of vaccination.

Results: Out of 184 subjects who participated in the study, 161 patients suffered pain at the injection site after the first dose, of which 90% of the participants were relieved and 93 suffered after the second dose, of which 95% of the participants were relieved with little medical intervention in the form of analgesics. Almost 50% of participants suffered fever and fatigue and <30% of the participants suffered headache, chills, and giddiness within 2 days of the first dose. Lump and warmth at the injection site are common with any vaccination and the incidence was <10% of the participants. All the symptoms subsided with intervention with paracetamol.

Conclusion: The safety of the vaccine is evident from this study. Through this study, we hope that the administration of the vaccination can be conducted doubtlessly to fight COVID-19 and any symptoms that arise eventually can be monitored and treated.

Key words: Vaccinations; Side Effects; Adverse Drug Reactions; Fever; Post-vaccination Symptoms


 
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How to Cite this Article
Pubmed Style

Elango A, Kannan N, Anandan I, Mohan SK. A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study. Natl J Physiol Pharm Pharmacol. 2024; 14(10): 2028-2034. doi:10.5455/njppp.2024.14.05211202418052024


Web Style

Elango A, Kannan N, Anandan I, Mohan SK. A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study. https://www.njppp.com/?mno=201563 [Access: February 12, 2025]. doi:10.5455/njppp.2024.14.05211202418052024


AMA (American Medical Association) Style

Elango A, Kannan N, Anandan I, Mohan SK. A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study. Natl J Physiol Pharm Pharmacol. 2024; 14(10): 2028-2034. doi:10.5455/njppp.2024.14.05211202418052024



Vancouver/ICMJE Style

Elango A, Kannan N, Anandan I, Mohan SK. A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study. Natl J Physiol Pharm Pharmacol. (2024), [cited February 12, 2025]; 14(10): 2028-2034. doi:10.5455/njppp.2024.14.05211202418052024



Harvard Style

Elango, A., Kannan, . N., Anandan, . I. & Mohan, . S. K. (2024) A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study. Natl J Physiol Pharm Pharmacol, 14 (10), 2028-2034. doi:10.5455/njppp.2024.14.05211202418052024



Turabian Style

Elango, Anitha, Neevedha Kannan, Isswariya Anandan, and Surapaneni Krishna Mohan. 2024. A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (10), 2028-2034. doi:10.5455/njppp.2024.14.05211202418052024



Chicago Style

Elango, Anitha, Neevedha Kannan, Isswariya Anandan, and Surapaneni Krishna Mohan. "A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 2028-2034. doi:10.5455/njppp.2024.14.05211202418052024



MLA (The Modern Language Association) Style

Elango, Anitha, Neevedha Kannan, Isswariya Anandan, and Surapaneni Krishna Mohan. "A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study." National Journal of Physiology, Pharmacy and Pharmacology 14.10 (2024), 2028-2034. Print. doi:10.5455/njppp.2024.14.05211202418052024



APA (American Psychological Association) Style

Elango, A., Kannan, . N., Anandan, . I. & Mohan, . S. K. (2024) A survey to determine the safety of covishield in post-vaccinated health-care professionals and workers at tertiary care center – A retrospective cohort study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (10), 2028-2034. doi:10.5455/njppp.2024.14.05211202418052024