E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research
Online Published: 11 Jun 2024
 


Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study

Ashwin Budihal, Madhuri M Gudikote, Naveen Kumar P, Vidya K R.


Abstract
Background: The varicella-zoster virus, which is known to lie dormant in the dorsal root ganglia after primary chickenpox infection or immunization, and in rare instances, intrauterine infection, is the source of the common viral infection known as herpes zoster (HZ). In healthy people, the illness usually goes away on its own, but in severely immunocompromised patients, it can cause persistent debilitation through multi-dermatomal, severe, vesiculo-pustular, nodular, crusted, and ecthymatous manifestations.

Aims and Objectives: The aim of this study was to better understand the clinical profile and epidemiological patterns of HZ and various postherpetic complications.

Materials and Methods: A prospective cross-sectional study was conducted at a tertiary care hospital in Karnataka for 24 months during August 2013–August 2015. Seventy-five patients with HZ and postherpetic complications attending the dermatology outpatient department were included in the study. Pre-existing comorbidities and patient details were recorded. The Hayes and Patterson Visual Analog Scale (VAS) was used to record the kind, duration, and intensity of the pain.

Results: The current cross-sectional study was done in a tertiary care hospital, and a total of 75 patients were considered for the study. The youngest patient was a 12-year-old male and the eldest patient was a 90-year-old male. The average age of patients was 52.45 ± 12.5 years. Cutaneous examination showed erythema (84%) and vesicles (84%). The intensity of pain was classified based on the VAS. About 54.6% of patients had a moderate degree of pain.

Conclusion: Acute vesicles with erythema and radicular pain with a unilateral dermatomal distribution are the most typical presentation of HZ infection, and they are most frequently seen in the thoracic area.

Key words: Herpes Zoster; Clinical Profile; Visual Analog Scale


 
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How to Cite this Article
Pubmed Style

Budihal A, Gudikote MM, P NK, R VK. Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study. Natl J Physiol Pharm Pharmacol. 2024; 14(10): 2063-2066. doi:10.5455/njppp.2024.14.05200202431052024


Web Style

Budihal A, Gudikote MM, P NK, R VK. Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study. https://www.njppp.com/?mno=200569 [Access: January 18, 2025]. doi:10.5455/njppp.2024.14.05200202431052024


AMA (American Medical Association) Style

Budihal A, Gudikote MM, P NK, R VK. Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study. Natl J Physiol Pharm Pharmacol. 2024; 14(10): 2063-2066. doi:10.5455/njppp.2024.14.05200202431052024



Vancouver/ICMJE Style

Budihal A, Gudikote MM, P NK, R VK. Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study. Natl J Physiol Pharm Pharmacol. (2024), [cited January 18, 2025]; 14(10): 2063-2066. doi:10.5455/njppp.2024.14.05200202431052024



Harvard Style

Budihal, A., Gudikote, . M. M., P, . N. K. & R, . V. K. (2024) Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study. Natl J Physiol Pharm Pharmacol, 14 (10), 2063-2066. doi:10.5455/njppp.2024.14.05200202431052024



Turabian Style

Budihal, Ashwin, Madhuri M Gudikote, Naveen Kumar P, and Vidya K R. 2024. Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (10), 2063-2066. doi:10.5455/njppp.2024.14.05200202431052024



Chicago Style

Budihal, Ashwin, Madhuri M Gudikote, Naveen Kumar P, and Vidya K R. "Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 2063-2066. doi:10.5455/njppp.2024.14.05200202431052024



MLA (The Modern Language Association) Style

Budihal, Ashwin, Madhuri M Gudikote, Naveen Kumar P, and Vidya K R. "Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study." National Journal of Physiology, Pharmacy and Pharmacology 14.10 (2024), 2063-2066. Print. doi:10.5455/njppp.2024.14.05200202431052024



APA (American Psychological Association) Style

Budihal, A., Gudikote, . M. M., P, . N. K. & R, . V. K. (2024) Clinical and epidemiological profile of herpes zoster cases and its complications: A prospective study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (10), 2063-2066. doi:10.5455/njppp.2024.14.05200202431052024