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Original Research
Online Published: 31 Mar 2024
 


Semen oxidative stress in male infertility: A case–control study

Sandhya Sharma, Karunakar Kota, Nilay Devendrabhai Pandya, Manjinder Kaur, Vamshi Kota.


Abstract
Background: Though a certain level of free radicals is required for the proper maturation of a sperm, excessive level of free radicals is believed to be a major factor contributing to male infertility.

Aims and Objectives: This study aimed to identify the level of oxidative stress (OS) among infertile males.

Materials and Methods: In the present study, semen Malondialdehyde (MDA) level, as an OS marker was studied in 96 normozoospermics who were taken as controls, and the values were compared separately to semen MDA levels of 75 oligozoospermics, 36 azoospermics and 19 necrozoospermics using unpaired t-test. P < 0.05 was considered statistically significant.

Results: The study showed significantly higher semen MDA levels in oligozoospermics and necrozoospermics compared to normozoospermics, but azoospermics did not show a statistically significant difference.

Conclusion: We concluded that excessive OS can be one of the major contributing factors for male infertility.

Key words: Oxidative Stress; Semen Malondialdehyde; Infertility


 
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How to Cite this Article
Pubmed Style

Sharma S, Kota K, Pandya ND, Kaur M, Kota V. Semen oxidative stress in male infertility: A case–control study. Natl J Physiol Pharm Pharmacol. 2024; 14(9): 1784-1787. doi:10.5455/njppp.2024.14.03111202424032024

Web Style

Sharma S, Kota K, Pandya ND, Kaur M, Kota V. Semen oxidative stress in male infertility: A case–control study. https://www.njppp.com/?mno=193031 [Access: September 12, 2024]. doi:10.5455/njppp.2024.14.03111202424032024

AMA (American Medical Association) Style

Sharma S, Kota K, Pandya ND, Kaur M, Kota V. Semen oxidative stress in male infertility: A case–control study. Natl J Physiol Pharm Pharmacol. 2024; 14(9): 1784-1787. doi:10.5455/njppp.2024.14.03111202424032024


Vancouver/ICMJE Style

Sharma S, Kota K, Pandya ND, Kaur M, Kota V. Semen oxidative stress in male infertility: A case–control study. Natl J Physiol Pharm Pharmacol. (2024), [cited September 12, 2024]; 14(9): 1784-1787. doi:10.5455/njppp.2024.14.03111202424032024


Harvard Style

Sharma, S., Kota, . K., Pandya, . N. D., Kaur, . M. & Kota, . V. (2024) Semen oxidative stress in male infertility: A case–control study. Natl J Physiol Pharm Pharmacol, 14 (9), 1784-1787. doi:10.5455/njppp.2024.14.03111202424032024


Turabian Style

Sharma, Sandhya, Karunakar Kota, Nilay Devendrabhai Pandya, Manjinder Kaur, and Vamshi Kota. 2024. Semen oxidative stress in male infertility: A case–control study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (9), 1784-1787. doi:10.5455/njppp.2024.14.03111202424032024


Chicago Style

Sharma, Sandhya, Karunakar Kota, Nilay Devendrabhai Pandya, Manjinder Kaur, and Vamshi Kota. "Semen oxidative stress in male infertility: A case–control study." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 1784-1787. doi:10.5455/njppp.2024.14.03111202424032024


MLA (The Modern Language Association) Style

Sharma, Sandhya, Karunakar Kota, Nilay Devendrabhai Pandya, Manjinder Kaur, and Vamshi Kota. "Semen oxidative stress in male infertility: A case–control study." National Journal of Physiology, Pharmacy and Pharmacology 14.9 (2024), 1784-1787. Print. doi:10.5455/njppp.2024.14.03111202424032024


APA (American Psychological Association) Style

Sharma, S., Kota, . K., Pandya, . N. D., Kaur, . M. & Kota, . V. (2024) Semen oxidative stress in male infertility: A case–control study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (9), 1784-1787. doi:10.5455/njppp.2024.14.03111202424032024




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