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2024, Vol: 14, Issue: 10
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Original Research
Online Published: 19 Jun 2024
 


Obesity as a risk factor for endometrial carcinoma

Divyapriya R, Vasanthakumari K P, S Lakshmi Vinodh, Jaimie T Jacob.


Abstract
Background: In underdeveloped nations, endometrial cancer (EC) ranks second in frequency among gynecological cancers. Extended periods of exposure to high levels of estrogen, whether from external or internal sources, are the primary cause of EC. An increased risk of EC is linked to obesity.

Aims and Objectives: Our objective is to investigate the relationship between obesity and EC that has been histopathologically verified.

Materials and Methods: This study uses a case–control design. Seventy patients who had post-hysterectomy confirming histological reports of EC were considered cases. Of 70 age-matched patients ranging from 30 to 80 years with non-malignant histopathology reports from endometrial sampling were the controls.

Results: Out of 70 cases, 21.4% were overweight and 55.7% were obese. The mean body mass index was 25.9 kg/m2 among the cases and 23.9 kg/m2 among the controls. With an odds ratio of 2.1 (95% confidence intervals-1.1–4.2), the findings indicated a statistically significant correlation between obesity and EC.

Conclusion: Obesity and EC were found to be significantly associated. EC has also been linked to diabetes and polycystic ovary syndrome.

Key words: Index of Body Mass; Estrogen; Endometrial Cancer; Obesity


 
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How to Cite this Article
Pubmed Style

R D, P VK, Vinodh SL, Jacob JT. Obesity as a risk factor for endometrial carcinoma. Natl J Physiol Pharm Pharmacol. 2024; 14(10): 2096-2100. doi:10.5455/njppp.2024.14.01009202410062024

Web Style

R D, P VK, Vinodh SL, Jacob JT. Obesity as a risk factor for endometrial carcinoma. https://www.njppp.com/?mno=183876 [Access: October 03, 2024]. doi:10.5455/njppp.2024.14.01009202410062024

AMA (American Medical Association) Style

R D, P VK, Vinodh SL, Jacob JT. Obesity as a risk factor for endometrial carcinoma. Natl J Physiol Pharm Pharmacol. 2024; 14(10): 2096-2100. doi:10.5455/njppp.2024.14.01009202410062024


Vancouver/ICMJE Style

R D, P VK, Vinodh SL, Jacob JT. Obesity as a risk factor for endometrial carcinoma. Natl J Physiol Pharm Pharmacol. (2024), [cited October 03, 2024]; 14(10): 2096-2100. doi:10.5455/njppp.2024.14.01009202410062024


Harvard Style

R, D., P, . V. K., Vinodh, . S. L. & Jacob, . J. T. (2024) Obesity as a risk factor for endometrial carcinoma. Natl J Physiol Pharm Pharmacol, 14 (10), 2096-2100. doi:10.5455/njppp.2024.14.01009202410062024


Turabian Style

R, Divyapriya, Vasanthakumari K P, S Lakshmi Vinodh, and Jaimie T Jacob. 2024. Obesity as a risk factor for endometrial carcinoma. National Journal of Physiology, Pharmacy and Pharmacology, 14 (10), 2096-2100. doi:10.5455/njppp.2024.14.01009202410062024


Chicago Style

R, Divyapriya, Vasanthakumari K P, S Lakshmi Vinodh, and Jaimie T Jacob. "Obesity as a risk factor for endometrial carcinoma." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 2096-2100. doi:10.5455/njppp.2024.14.01009202410062024


MLA (The Modern Language Association) Style

R, Divyapriya, Vasanthakumari K P, S Lakshmi Vinodh, and Jaimie T Jacob. "Obesity as a risk factor for endometrial carcinoma." National Journal of Physiology, Pharmacy and Pharmacology 14.10 (2024), 2096-2100. Print. doi:10.5455/njppp.2024.14.01009202410062024


APA (American Psychological Association) Style

R, D., P, . V. K., Vinodh, . S. L. & Jacob, . J. T. (2024) Obesity as a risk factor for endometrial carcinoma. National Journal of Physiology, Pharmacy and Pharmacology, 14 (10), 2096-2100. doi:10.5455/njppp.2024.14.01009202410062024




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