E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


High-sensitivity C-reactive protein as a biomarker of cardiovascular events

Dhwani Bhaveshkumar Pandya, Bharat Bhetariya, Nayan Koitiya.

Abstract
Background: Development of high sensitivity CRP (Hs-CRP) assays has improved the role of this acute phase reactant in predicting the first cardiovascular events. Hs-CRP levels partially reflect the extent of myocardial necrosis and can be used to predict in hospital and long-term outcome in patients with acute myocardial infarction.

Aims and Objectives: The objectives of the study are to study and correlate increased level of Hs-CRP with various traditional risk factors such as age, sex, lifestyle, and comorbidities and to establish increased level of Hs-CRP as an independent marker for cardiovascular events.

Materials and Methods: A 100 patients’ prospective cross-sectional study was conducted at tertiary care center with traditional risk factors and existing cardiovascular diseases. Measurements of Hs-CRP levels were done with immunoturbidimetric methods with statistical correlation. The statistical analysis was done using IBM SPSS version 26 software.

Results: In total 100 patients, 67 patients had Hs-CRP value more than 3 mg/L where-as 33 patients had Hs-CRP value <3 mg/L, 32% of patients belonged to age group 51–60 years and majority 78% were male. Among all the individual life style parameters and traditional risk factor which were considered, five parameters, namely, sedentary life style, smoking, pre-existing hypertension, diabetes mellitus, and electrocardiogram changes were proved statistically significant and correlation between elevated high sensitivity C reactive protein and cardiovascular disease was proved statistically significant.

Conclusion: Hs-CRP is independent biomarker for cardiovascular disease and positive correlation was established between elevated level of Hs-CRP and major traditional risk factors such as sedentary life style, smoking, hypertension, and diabetes mellitus.

Key words: Myocardial Infarction; Biochemistry; Atherosclerosis; C Reactive Protein


 
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How to Cite this Article
Pubmed Style

Pandya DB, Bhetariya B, Koitiya N. High-sensitivity C-reactive protein as a biomarker of cardiovascular events. Natl J Physiol Pharm Pharmacol. 2024; 14(2): 210-212. doi:10.5455/njppp.2023.13.06292202328062023


Web Style

Pandya DB, Bhetariya B, Koitiya N. High-sensitivity C-reactive protein as a biomarker of cardiovascular events. https://www.njppp.com/?mno=155184 [Access: January 31, 2024]. doi:10.5455/njppp.2023.13.06292202328062023


AMA (American Medical Association) Style

Pandya DB, Bhetariya B, Koitiya N. High-sensitivity C-reactive protein as a biomarker of cardiovascular events. Natl J Physiol Pharm Pharmacol. 2024; 14(2): 210-212. doi:10.5455/njppp.2023.13.06292202328062023



Vancouver/ICMJE Style

Pandya DB, Bhetariya B, Koitiya N. High-sensitivity C-reactive protein as a biomarker of cardiovascular events. Natl J Physiol Pharm Pharmacol. (2024), [cited January 31, 2024]; 14(2): 210-212. doi:10.5455/njppp.2023.13.06292202328062023



Harvard Style

Pandya, D. B., Bhetariya, . B. & Koitiya, . N. (2024) High-sensitivity C-reactive protein as a biomarker of cardiovascular events. Natl J Physiol Pharm Pharmacol, 14 (2), 210-212. doi:10.5455/njppp.2023.13.06292202328062023



Turabian Style

Pandya, Dhwani Bhaveshkumar, Bharat Bhetariya, and Nayan Koitiya. 2024. High-sensitivity C-reactive protein as a biomarker of cardiovascular events. National Journal of Physiology, Pharmacy and Pharmacology, 14 (2), 210-212. doi:10.5455/njppp.2023.13.06292202328062023



Chicago Style

Pandya, Dhwani Bhaveshkumar, Bharat Bhetariya, and Nayan Koitiya. "High-sensitivity C-reactive protein as a biomarker of cardiovascular events." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 210-212. doi:10.5455/njppp.2023.13.06292202328062023



MLA (The Modern Language Association) Style

Pandya, Dhwani Bhaveshkumar, Bharat Bhetariya, and Nayan Koitiya. "High-sensitivity C-reactive protein as a biomarker of cardiovascular events." National Journal of Physiology, Pharmacy and Pharmacology 14.2 (2024), 210-212. Print. doi:10.5455/njppp.2023.13.06292202328062023



APA (American Psychological Association) Style

Pandya, D. B., Bhetariya, . B. & Koitiya, . N. (2024) High-sensitivity C-reactive protein as a biomarker of cardiovascular events. National Journal of Physiology, Pharmacy and Pharmacology, 14 (2), 210-212. doi:10.5455/njppp.2023.13.06292202328062023