Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study

Santosh Madhao Kayande; Urjita Zingade; Sheetal Madhav Munde; Anupam Suhas Khare

doi:10.5455/njppp.2023.13.05285202308062023

2026, Vol: 16, Issue: 2

16 / 2Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

NJPPP Manuscript Submission Form
Title Page

« Previous Article

Original Research
Online Published: 20 Jun 2023

Natl J Physiol Pharm Pharmacol. 2024; 14(1): 149-152

doi: 10.5455/njppp.2023.13.05285202308062023

Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study

Santosh Madhao Kayande, Urjita Zingade, Sheetal Madhav Munde, Anupam Suhas Khare.

Abstract
Background: Hypothyroid or hyperthyroid state affects all the physiological systems including cardiovascular system, central nervous system, digestive system, and blood. Among all adverse changes, systolic blood pressure (SBP) can also be affected in patients with thyroid disorders.

Aims and Objectives: The present study was carried out to compare SBP in newly diagnosed patients of hypothyroidism, hyperthyroidism and age and gender matched euthyroid subjects and to assess correlation between Tri-iodothyronine (T3) level and resting SBP.

Materials and Methods: The present study was carried out in 90 female subjects in the age group of 30 to 45 years. Diagnosis of hypothyroidism and hyperthyroidism was based on both clinical and biochemical criteria. Subjects were divided in euthyroid, hypothyroid and hyperthyroid groups with each group containing 30 subjects. Resting SBP was measured in all the groups.

Results: Hyperthyroid group had significantly higher SBP as compared to euthyroid group and hypothyroid group. The difference in SBP between euthyroid and hypothyroid group was statistically non-significant. There was a significant correlation between Total T3 level and resting SBP.

Conclusion: Elevated levels of thyroid hormone increases the cardiac output by increasing heart rate and increasing force of contraction. This elevated cardiac output in hyperthyroid subject is reflected as increase in resting SBP. Hence, thyroid hormone concentration should be kept within normal limits by appropriate therapeutic measures so as to prevent ill effects of resultant elevated SBP.

Key words: Systolic Blood Pressure; Euthyroid; Hypothyroid; Hyperthyroid

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Santosh Madhao Kayande Articles by Urjita Zingade Articles by Sheetal Madhav Munde Articles by Anupam Suhas Khare
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Kayande SM, Zingade U, Munde SM, Khare AS. Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study. Natl J Physiol Pharm Pharmacol. 2024; 14(1): 149-152.

doi:10.5455/njppp.2023.13.05285202308062023

Web Style

Kayande SM, Zingade U, Munde SM, Khare AS. Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study. https://www.njppp.com/?mno=154586 [Access: June 27, 2026].

doi:10.5455/njppp.2023.13.05285202308062023

AMA (American Medical Association) Style

Kayande SM, Zingade U, Munde SM, Khare AS. Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study. Natl J Physiol Pharm Pharmacol. 2024; 14(1): 149-152.

doi:10.5455/njppp.2023.13.05285202308062023

Vancouver/ICMJE Style

Kayande SM, Zingade U, Munde SM, Khare AS. Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study. Natl J Physiol Pharm Pharmacol. (2024), [cited June 27, 2026]; 14(1): 149-152.

doi:10.5455/njppp.2023.13.05285202308062023

Harvard Style

Kayande, S. M., Zingade, . U., Munde, . S. M. & Khare, . A. S. (2024) Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study. Natl J Physiol Pharm Pharmacol, 14 (1), 149-152.

doi:10.5455/njppp.2023.13.05285202308062023

Turabian Style

Kayande, Santosh Madhao, Urjita Zingade, Sheetal Madhav Munde, and Anupam Suhas Khare. 2024. Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (1), 149-152.

doi:10.5455/njppp.2023.13.05285202308062023

Chicago Style

Kayande, Santosh Madhao, Urjita Zingade, Sheetal Madhav Munde, and Anupam Suhas Khare. "Does altered thyroid hormone status affect resting systolic blood pressure significantly in premenopausal women? - A cross-sectional comparative study." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 149-152.

doi:10.5455/njppp.2023.13.05285202308062023

MLA (The Modern Language Association) Style

doi:10.5455/njppp.2023.13.05285202308062023

APA (American Psychological Association) Style

doi:10.5455/njppp.2023.13.05285202308062023

About National Journal of Physiology, Pharmacy and Pharmacology

Contact Information

How to cite this article