Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health

Preeti Kanawjia; Saurabh Saha; Atosh Kumar

doi:10.5455/njppp.2023.13.01025202318012023

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Original Research
Online Published: 24 Jan 2023

Natl J Physiol Pharm Pharmacol. 2023; 13(2023, Vol: 13, Issue: 8): 1710-1715

doi: 10.5455/njppp.2023.13.01025202318012023

Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health

Preeti Kanawjia, Saurabh Saha, Atosh Kumar.

Abstract
Background: A parameter of arterial stiffness, the pulse pressure (PP) gets adversely affected by serum low-density lipoprotein but to know how do other indicators of cardiovascular health such as cholesterol ratio, adiposity, and serum endothelin are correlated to it, we planned this study.

Aims and Objectives: The aim of the study was to study the correlation of PP to demographic, anthropometric, hemodynamic, and biochemical variables.

Materials and Methods: This was an analytical, observational, and pilot study with 30 overweight/obese subjects as cases and 30 non-obese subjects as controls. Informed consent was duly taken. History and clinical examination helped to exclude cases with secondary cause of abnormal blood flow. Blood pressure measurement along with venous blood sampling for biochemical tests was done.

Results: The two groups varied significantly in age, in hemodynamic parameters (systolic blood pressure [SBP], diastolic blood pressure and PP), and in anthropometric measurements (waist to hip ratio [WHR], body mass index) (P < 0.001). The lipid profile did not differ significantly in the two groups except the cholesterol ratio (P = 0.001) but it was not significantly correlated to PP. A good proportion of cases had raised PP in comparison to control who mostly had low PP. No significant difference in serum endothelin levels was observed. A significant positive correlation of PP with SBP and WHR in both groups (weakened on controlling the age variable), and with age, only in cases was recorded.

Conclusion: Visceral adiposity, SBP, and ageing are independent predictors of PP but with no endothelial damage. Partial correlation revealed a major role of ageing in causing arterial stiffness.

Key words: Endothelin 1; Pulse Pressure; Abdominal Obesity

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Pubmed Style

Kanawjia P, Saha S, Kumar A. Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health. Natl J Physiol Pharm Pharmacol. 2023; 13(2023, Vol: 13, Issue: 8): 1710-1715. doi:10.5455/njppp.2023.13.01025202318012023

Web Style

Kanawjia P, Saha S, Kumar A. Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health. https://www.njppp.com/?mno=139600 [Access: November 02, 2024]. doi:10.5455/njppp.2023.13.01025202318012023

AMA (American Medical Association) Style

Kanawjia P, Saha S, Kumar A. Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health. Natl J Physiol Pharm Pharmacol. 2023; 13(2023, Vol: 13, Issue: 8): 1710-1715. doi:10.5455/njppp.2023.13.01025202318012023

Vancouver/ICMJE Style

Kanawjia P, Saha S, Kumar A. Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health. Natl J Physiol Pharm Pharmacol. (2023), [cited November 02, 2024]; 13(2023, Vol: 13, Issue: 8): 1710-1715. doi:10.5455/njppp.2023.13.01025202318012023

Harvard Style

Kanawjia, P., Saha, . S. & Kumar, . A. (2023) Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health. Natl J Physiol Pharm Pharmacol, 13 (2023, Vol: 13, Issue: 8), 1710-1715. doi:10.5455/njppp.2023.13.01025202318012023

Turabian Style

Kanawjia, Preeti, Saurabh Saha, and Atosh Kumar. 2023. Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health. National Journal of Physiology, Pharmacy and Pharmacology, 13 (2023, Vol: 13, Issue: 8), 1710-1715. doi:10.5455/njppp.2023.13.01025202318012023

Chicago Style

Kanawjia, Preeti, Saurabh Saha, and Atosh Kumar. "Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 1710-1715. doi:10.5455/njppp.2023.13.01025202318012023

MLA (The Modern Language Association) Style

Kanawjia, Preeti, Saurabh Saha, and Atosh Kumar. "Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health." National Journal of Physiology, Pharmacy and Pharmacology 13.2023, Vol: 13, Issue: 8 (2023), 1710-1715. Print. doi:10.5455/njppp.2023.13.01025202318012023

APA (American Psychological Association) Style

Kanawjia, P., Saha, . S. & Kumar, . A. (2023) Correlation of pulse pressure to demographic, anthropometric, hemodynamic, and biochemical variables governing cardiovascular health. National Journal of Physiology, Pharmacy and Pharmacology, 13 (2023, Vol: 13, Issue: 8), 1710-1715. doi:10.5455/njppp.2023.13.01025202318012023

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