Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension

Sudha B Sreenivas; Vinitha K R

doi:10.5455/njppp.2020.10.05137202029052020

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Original Research
Online Published: 06 Jun 2020

Natl J Physiol Pharm Pharmacol. 2020; 10(9): 740-743

doi: 10.5455/njppp.2020.10.05137202029052020

Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension

Sudha B Sreenivas, Vinitha K R.

Abstract
Background: Elevated intraocular pressure (IOP) and reduced ocular perfusion pressure (OPP) are major risk factors in the development and progression of glaucoma. Although both obesity and prehypertension are risk factors in elevating IOP, very few studies have analyzed the effects of obesity on IOP and OPP in pre-hypertensive individuals.

Aim and Objective: This study aims to assess the effects of body mass index (BMI) on IOP and OPP in pre-hypertensive individuals.

Materials and Methods: A total of 100 voluntary participants with prehypertension (systolic blood pressure of 120139 mmHg or diastolic blood pressure of 8089 mmHg) in the age group of 2050 years were selected from an ophthalmology clinic in Mysuru. They were categorized into two groups based on their BMI into obese and non-obese pre-hypertensive groups. IOP was recorded using rebound tonometer and OPP was calculated.

Results: Statistically significant elevation in IOP and reduction in OPP values of both the eyes were observed in obese pre-hypertensive group.

Conclusion: Obesity compounds the effect of prehypertension on IOP and OPP probably by early disruption of the autoregulatory mechanisms that maintain constant ocular blood flow. Understanding of the complex relationship between IOP and OPP in obese, pre-hypertensive population might help in preventing the risk of developing glaucoma.

Key words: Body Mass Index; Intraocular Pressure; Ocular Perfusion Pressure; Prehypertension

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Pubmed Style

Sreenivas SB, R VK. Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension. Natl J Physiol Pharm Pharmacol. 2020; 10(9): 740-743. doi:10.5455/njppp.2020.10.05137202029052020

Web Style

Sreenivas SB, R VK. Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension. https://www.njppp.com/?mno=110371 [Access: November 02, 2024]. doi:10.5455/njppp.2020.10.05137202029052020

AMA (American Medical Association) Style

Sreenivas SB, R VK. Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension. Natl J Physiol Pharm Pharmacol. 2020; 10(9): 740-743. doi:10.5455/njppp.2020.10.05137202029052020

Vancouver/ICMJE Style

Sreenivas SB, R VK. Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension. Natl J Physiol Pharm Pharmacol. (2020), [cited November 02, 2024]; 10(9): 740-743. doi:10.5455/njppp.2020.10.05137202029052020

Harvard Style

Sreenivas, S. B. & R, . V. K. (2020) Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension. Natl J Physiol Pharm Pharmacol, 10 (9), 740-743. doi:10.5455/njppp.2020.10.05137202029052020

Turabian Style

Sreenivas, Sudha B, and Vinitha K R. 2020. Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension. National Journal of Physiology, Pharmacy and Pharmacology, 10 (9), 740-743. doi:10.5455/njppp.2020.10.05137202029052020

Chicago Style

Sreenivas, Sudha B, and Vinitha K R. "Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension." National Journal of Physiology, Pharmacy and Pharmacology 10 (2020), 740-743. doi:10.5455/njppp.2020.10.05137202029052020

MLA (The Modern Language Association) Style

Sreenivas, Sudha B, and Vinitha K R. "Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension." National Journal of Physiology, Pharmacy and Pharmacology 10.9 (2020), 740-743. Print. doi:10.5455/njppp.2020.10.05137202029052020

APA (American Psychological Association) Style

Sreenivas, S. B. & R, . V. K. (2020) Effects of body mass index on intraocular pressure and ocular perfusion pressure in individuals with prehypertension. National Journal of Physiology, Pharmacy and Pharmacology, 10 (9), 740-743. doi:10.5455/njppp.2020.10.05137202029052020

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