E-ISSN 2231-3206 | ISSN 2320-4672
 
2024, Vol: 14, Issue: 9
14 / 9Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles
Required files to be uploaded

Authorship Declaration

Original Research
Online Published: 15 May 2023
 


Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital

Bindu J Jadeja, Neeta Khokhar, Gaurishanker Shrimali.


Abstract
Background: Urinary tract infection (UTI) is a common health problem in both community and nosocomial settings. However, the predisposing factors which are responsible for production of extended spectrum beta-lactamase (ESBL) and carbapenem-resistant Enterobacteriaceae makes the treatment option narrow and cause multidrug resistance.

Aim and Objectives: This study demonstrate various risk factors associated with multidrug resistance in Enterobacteriaceae from UTI at tertiary care center in Gujarat.

Material and Methods: A retrospective observational study was conducted at a tertiary-care hospital. Urine samples were received from various departments and outpatient department (OPD). Organisms from Enterobacteriaceae group were isolated and identified by various biochemical methods. ESBL and Carbapenemase producing organisms were then processed for Antibiotic susceptibility test as per CLSI guideline.

Results: A total of 196 Enterobacteriaceae organisms were isolated from processed urine samples of tertiary care Hospitals. The most prevalent in people aged 45–65 years (36%) followed by those aged 17–30 (22%) years. UTI due to ESBL and Carbapenemase producer are more isolated in female (28%, 11%) as compare to male (16%, 6%). Indoor patients had higher prevalence of ESBL (29%) and carbapenemases (10%) isolation compare to OPD patient (ESBL-15%, Carbapenemases-7%) and among them most common ward was medicine department. The most common predisposing factor was catheterization followed by diabetes mellitus and obstructive uropathy.

Conclusion: High prevalence of ESBL and Carbapenemase producing Enterobacteriaceae is found in Indoor patients than OPD patients. Most of these patients are from Medicine department. Catheterization is the most common risk factor associated with ESBL and carbapenemase producing organism.

Key words: Enterobacteriaceae; Extended Spectrum Beta-Lactamase; Carbapenem-Resistant Enterobacteriaceae; Urinary Tract Infection


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Bindu J Jadeja
Articles by Neeta Khokhar
Articles by Gaurishanker Shrimali
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Jadeja BJ, Khokhar N, Shrimali G. Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital. Natl J Physiol Pharm Pharmacol. 2023; 13(6): 1304-1307. doi:10.5455/njppp.2023.13.04212202302052023

Web Style

Jadeja BJ, Khokhar N, Shrimali G. Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital. https://www.njppp.com/?mno=150228 [Access: September 13, 2024]. doi:10.5455/njppp.2023.13.04212202302052023

AMA (American Medical Association) Style

Jadeja BJ, Khokhar N, Shrimali G. Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital. Natl J Physiol Pharm Pharmacol. 2023; 13(6): 1304-1307. doi:10.5455/njppp.2023.13.04212202302052023


Vancouver/ICMJE Style

Jadeja BJ, Khokhar N, Shrimali G. Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital. Natl J Physiol Pharm Pharmacol. (2023), [cited September 13, 2024]; 13(6): 1304-1307. doi:10.5455/njppp.2023.13.04212202302052023


Harvard Style

Jadeja, B. J., Khokhar, . N. & Shrimali, . G. (2023) Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital. Natl J Physiol Pharm Pharmacol, 13 (6), 1304-1307. doi:10.5455/njppp.2023.13.04212202302052023


Turabian Style

Jadeja, Bindu J, Neeta Khokhar, and Gaurishanker Shrimali. 2023. Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital. National Journal of Physiology, Pharmacy and Pharmacology, 13 (6), 1304-1307. doi:10.5455/njppp.2023.13.04212202302052023


Chicago Style

Jadeja, Bindu J, Neeta Khokhar, and Gaurishanker Shrimali. "Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 1304-1307. doi:10.5455/njppp.2023.13.04212202302052023


MLA (The Modern Language Association) Style

Jadeja, Bindu J, Neeta Khokhar, and Gaurishanker Shrimali. "Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital." National Journal of Physiology, Pharmacy and Pharmacology 13.6 (2023), 1304-1307. Print. doi:10.5455/njppp.2023.13.04212202302052023


APA (American Psychological Association) Style

Jadeja, B. J., Khokhar, . N. & Shrimali, . G. (2023) Risk factors for extended-spectrum beta-lactamase- and carbapenem- resistant Enterobacteriaceae in patients with urinary tract infection from a tertiary care hospital. National Journal of Physiology, Pharmacy and Pharmacology, 13 (6), 1304-1307. doi:10.5455/njppp.2023.13.04212202302052023




Most Viewed Articles
Most Accessed Articles

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract » doi: 10.5455/njppp.2013.3.109-114

    •
    Most Downloaded
    Top Downloaded Articles

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Evaluation of potential drug-drug interaction in indoor patients of pediatric department of tertiary care hospital
    Simran Patel, Mayur Chaudhari, Nrupal Patel
    Natl J Physiol Pharm Pharmacol. 2019; 9(10): 1012-1016
    » Abstract » doi: 10.5455/njppp.2019.9.0725209072019

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract » doi: 10.5455/njppp.2011.1.1-8

    •
    Most Cited Articles
    Most Cited Articles

    About National Journal of Physiology, Pharmacy and Pharmacology

      National Journal of Physiology, Pharmacy and Pharmacology is a monthly peer reviewed journal.  The journal is having open access polic ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Publisher

    publishernjppp@gmail.com

     

    Editorial query

    editornjppp1@gmail.com

    MOB - 8780040272

     

     

     
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Copyright Information
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Open Access Policy
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use