E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Study of developing tracheal cartilage under light microscope

Parul S Damor, Nileshkumar H Patel.

Abstract
Background: Airway formation is one of the earliest events in development of respiratory system. However, maturation of airway continues well in post-natal life. The trachea has framework of incomplete ring of hyaline cartilage united by fibrous tissue and smooth muscle through which air conduction takes place. The trachea-bronchial mucosa is target for host of airborne toxic agents; bacterial and viral agents, allergens, reactive gases, aerosols, and irritant particles. This fascinates many workers for detailed study of epithelium or lining air passage.

Aims and Objectives: The present study was undertaken to document normal developmental microscopic structure of tracheal cartilage in fetuses of different age group (gestational ages between 12th and 40th weeks) and to compare the difference between different age groups.

Materials and Methods: Tissues from trachea of various age group fetuses were collected, processed, and stained with H and E and Masson’s trichrome.

Results: Development of tracheal cartilage was observed into three trimesters. The 2nd and 3rd trimesters were further divided in the early 2nd (13th–16th weeks), mid-2nd (17th–20th weeks), late 2nd (21st–24th weeks), early 3rd (25th–28th weeks), mid-3rd (29th–32nd weeks), and late 3rd (33rd–40th weeks) phases.

Conclusion: Perichondrium of cartilage had shown well-marked outer fibrous layer with increased vascularity by late 2nd to early 3rd trimester. Well-marked inner cellular layer of perichondrium was noticed by 3rd trimester, while cartilage had shown active chondrocytes by late 2nd to early 3rd trimester. At the late 3rd trimester, typical hyaline cartilage had shown chondrocytes in cell nest surrounded by territorial matrix.

Key words: Microscopic Structure; Developmental Study; Human Tracheal Cartilage


 
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Pubmed Style

Damor PS, Patel NH. Study of developing tracheal cartilage under light microscope. Natl J Physiol Pharm Pharmacol. 2023; 13(1): 124-128. doi:10.5455/njppp.2023.13.11519202214112022


Web Style

Damor PS, Patel NH. Study of developing tracheal cartilage under light microscope. https://www.njppp.com/?mno=127128 [Access: February 01, 2023]. doi:10.5455/njppp.2023.13.11519202214112022


AMA (American Medical Association) Style

Damor PS, Patel NH. Study of developing tracheal cartilage under light microscope. Natl J Physiol Pharm Pharmacol. 2023; 13(1): 124-128. doi:10.5455/njppp.2023.13.11519202214112022



Vancouver/ICMJE Style

Damor PS, Patel NH. Study of developing tracheal cartilage under light microscope. Natl J Physiol Pharm Pharmacol. (2023), [cited February 01, 2023]; 13(1): 124-128. doi:10.5455/njppp.2023.13.11519202214112022



Harvard Style

Damor, P. S. & Patel, . N. H. (2023) Study of developing tracheal cartilage under light microscope. Natl J Physiol Pharm Pharmacol, 13 (1), 124-128. doi:10.5455/njppp.2023.13.11519202214112022



Turabian Style

Damor, Parul S, and Nileshkumar H Patel. 2023. Study of developing tracheal cartilage under light microscope. National Journal of Physiology, Pharmacy and Pharmacology, 13 (1), 124-128. doi:10.5455/njppp.2023.13.11519202214112022



Chicago Style

Damor, Parul S, and Nileshkumar H Patel. "Study of developing tracheal cartilage under light microscope." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 124-128. doi:10.5455/njppp.2023.13.11519202214112022



MLA (The Modern Language Association) Style

Damor, Parul S, and Nileshkumar H Patel. "Study of developing tracheal cartilage under light microscope." National Journal of Physiology, Pharmacy and Pharmacology 13.1 (2023), 124-128. Print. doi:10.5455/njppp.2023.13.11519202214112022



APA (American Psychological Association) Style

Damor, P. S. & Patel, . N. H. (2023) Study of developing tracheal cartilage under light microscope. National Journal of Physiology, Pharmacy and Pharmacology, 13 (1), 124-128. doi:10.5455/njppp.2023.13.11519202214112022