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Original Research Open Access


Modulation of immune responses in stress by vestibular stimulation

Archana Rajagopalan, Sai Sailesh Kumar, Minu Johny, Joseph Kurien Mukkadan.

Abstract
Background: We hypothesized that stress induced suppression of immunity may be prevented by vestibular stimulation by inhibiting the stress axes.

Aims and Objectives: The present study was undertaken to assess effectiveness of vestibular stimulation in the modulation of immune responses in stress.

Materials and Methods: A total of 240 healthy college students were randomly divided into four groups control male and female group and vestibular male and female groups with 60 participants in each group. Vestibular stimulation was administered by making the participants to swing on a swing in back to front direction, according to their comfort. After recording base line values, vestibular stimulation was administered to the intervention groups, and post-intervention values were collected during regular classes and during pre-examination period. Blood cell count was performed using Sysmex Machine (Model Sysmex XP 100) (an automatic multi parameter blood cell counter) manufactured by Sysmex India Pvt. Ltd.

Results: Vestibular stimulation limited stress induced changes in total leukocyte count, neutrophil, lymphocyte, monocyte, eosinophil, and absolute eosinophil count, counts in both male and female intervention groups. Stress induced decrease was prevented in female intervention group.

Conclusion: Our study provides further evidence for beneficial effects of vestibular stimulation in limiting stress induced changes in immune responses.

Key words: Vestibular Stimulation; Immunity; Stress; White Blood Cells; College Students


 
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How to Cite this Article
Pubmed Style

Rajagopalan A, Kumar SS, Johny M, Mukkadan JK. Modulation of immune responses in stress by vestibular stimulation. Natl J Physiol Pharm Pharmacol. 2017; 7(11): 1259-1263. doi:10.5455/njppp.2017.7.0725724072017



Web Style

Rajagopalan A, Kumar SS, Johny M, Mukkadan JK. Modulation of immune responses in stress by vestibular stimulation. www.scopemed.org/?mno=271576 [Access: November 22, 2017]. doi:10.5455/njppp.2017.7.0725724072017



AMA (American Medical Association) Style

Rajagopalan A, Kumar SS, Johny M, Mukkadan JK. Modulation of immune responses in stress by vestibular stimulation. Natl J Physiol Pharm Pharmacol. 2017; 7(11): 1259-1263. doi:10.5455/njppp.2017.7.0725724072017



Vancouver/ICMJE Style

Rajagopalan A, Kumar SS, Johny M, Mukkadan JK. Modulation of immune responses in stress by vestibular stimulation. Natl J Physiol Pharm Pharmacol. (2017), [cited November 22, 2017]; 7(11): 1259-1263. doi:10.5455/njppp.2017.7.0725724072017



Harvard Style

Rajagopalan, A., Kumar, S. S., Johny, M. & Mukkadan, J. K. (2017) Modulation of immune responses in stress by vestibular stimulation. Natl J Physiol Pharm Pharmacol, 7 (11), 1259-1263. doi:10.5455/njppp.2017.7.0725724072017



Turabian Style

Rajagopalan, Archana, Sai Sailesh Kumar, Minu Johny, and Joseph Kurien Mukkadan. 2017. Modulation of immune responses in stress by vestibular stimulation. National Journal of Physiology, Pharmacy and Pharmacology, 7 (11), 1259-1263. doi:10.5455/njppp.2017.7.0725724072017



Chicago Style

Rajagopalan, Archana, Sai Sailesh Kumar, Minu Johny, and Joseph Kurien Mukkadan. "Modulation of immune responses in stress by vestibular stimulation." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 1259-1263. doi:10.5455/njppp.2017.7.0725724072017



MLA (The Modern Language Association) Style

Rajagopalan, Archana, Sai Sailesh Kumar, Minu Johny, and Joseph Kurien Mukkadan. "Modulation of immune responses in stress by vestibular stimulation." National Journal of Physiology, Pharmacy and Pharmacology 7.11 (2017), 1259-1263. Print. doi:10.5455/njppp.2017.7.0725724072017



APA (American Psychological Association) Style

Rajagopalan, A., Kumar, S. S., Johny, M. & Mukkadan, J. K. (2017) Modulation of immune responses in stress by vestibular stimulation. National Journal of Physiology, Pharmacy and Pharmacology, 7 (11), 1259-1263. doi:10.5455/njppp.2017.7.0725724072017



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