E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus

Danasegaran, Balaji P V, Shaik Khaja Moinuddin, Haja Abdul Nazeer.

Abstract
Background: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. Infections occur more commonly in patients with DM due to the hyperglycemic medium that increases the virulence of pathogen.

Aims and Objectives: The present study was aimed to determine the impact of poor glycemic control as a risk factor for symptomatic urinary tract infection (UTI) in diabetic patients with asymptomatic bacteriuria (ASB) during follow-up.

Materials and Methods: This was a cross-sectional observational study conducted at Vinayaka Missions Medical College on diabetic patients. Hemoglobin Alc (HbA1c) was quantified spectrophotometrically using HbA1c test kits. All participants were instructed strictly to collect midstream urine sample. Urine samples collected from participants were inoculated on blood agar and MacConkey agar and incubated for overnight at 370C. If growth occurs, organism was identified by standard microbiological procedures. Symptomatic UTI surveillance was done by instructing participants to contact research personnel if any new symptom/symptoms occurred (follow-up period 3 months) that suggested UTI.

Results: A total of 225 participants were included in the study and categorized as diabetic (n = 175) and non-diabetic as control group (n = 50). A total of 107 diabetic patients had <7 HbA1c levels, 12 (11.21%) urine specimens collected from these patients yielded bacterial growth. Sixty-eight patients had ≥7 HbA1c levels, 19 (27.94%) urine specimens collected from these patients yielded bacterial growth. Among the patients with <7 HbA1c levels, 16.6% of patients developed symptomatic UTI and among the patients with ≥7 HbA1c, 5 (26.3%) patients developed symptomatic UTI.

Conclusion: Poor glycemic control can show the impact on ASB to develop symptomatic UTI.

Key words: Poor Glycemic Control; Asymptomatic Bacteriuria; Urinary Tract Infection


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Danasegaran
Articles by Balaji P V
Articles by Shaik Khaja Moinuddin
Articles by Haja Abdul Nazeer
on Google
on Google Scholar
Article Statistics
 Viewed: 1356
Downloaded: 217


How to Cite this Article
Pubmed Style

, V BP, Moinuddin SK, Nazeer HA. Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus. Natl J Physiol Pharm Pharmacol. 2019; 9(10): 987-990. doi:10.5455/njppp.2019.9.0725717072019


Web Style

, V BP, Moinuddin SK, Nazeer HA. Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus. http://www.njppp.com/?mno=56763 [Access: February 15, 2020]. doi:10.5455/njppp.2019.9.0725717072019


AMA (American Medical Association) Style

, V BP, Moinuddin SK, Nazeer HA. Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus. Natl J Physiol Pharm Pharmacol. 2019; 9(10): 987-990. doi:10.5455/njppp.2019.9.0725717072019



Vancouver/ICMJE Style

, V BP, Moinuddin SK, Nazeer HA. Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus. Natl J Physiol Pharm Pharmacol. (2019), [cited February 15, 2020]; 9(10): 987-990. doi:10.5455/njppp.2019.9.0725717072019



Harvard Style

, V, . B. P., Moinuddin, . S. K. & Nazeer, . H. A. (2019) Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus. Natl J Physiol Pharm Pharmacol, 9 (10), 987-990. doi:10.5455/njppp.2019.9.0725717072019



Turabian Style

, Balaji P V, Shaik Khaja Moinuddin, and Haja Abdul Nazeer. 2019. Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus. National Journal of Physiology, Pharmacy and Pharmacology, 9 (10), 987-990. doi:10.5455/njppp.2019.9.0725717072019



Chicago Style

, Balaji P V, Shaik Khaja Moinuddin, and Haja Abdul Nazeer. "Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 987-990. doi:10.5455/njppp.2019.9.0725717072019



MLA (The Modern Language Association) Style

, Balaji P V, Shaik Khaja Moinuddin, and Haja Abdul Nazeer. "Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus." National Journal of Physiology, Pharmacy and Pharmacology 9.10 (2019), 987-990. Print. doi:10.5455/njppp.2019.9.0725717072019



APA (American Psychological Association) Style

, V, . B. P., Moinuddin, . S. K. & Nazeer, . H. A. (2019) Impact of hemoglobin A1c levels on asymptomatic bacteriuria in type 2 diabetes mellitus. National Journal of Physiology, Pharmacy and Pharmacology, 9 (10), 987-990. doi:10.5455/njppp.2019.9.0725717072019





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Evaluation of potential drug-drug interaction in indoor patients of pediatric department of tertiary care hospital
    Simran Patel, Mayur Chaudhari, Nrupal Patel
    Natl J Physiol Pharm Pharmacol. 2019; 9(10): 1012-1016
    » Abstract » doi: 10.5455/njppp.2019.9.0725209072019

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Most Cited Articles
  • Promoting active learning in respiratory physiology Positive student perception and improved outcomes
    Richa Thaman, Sukhjinder Dhillon, Sanjeev Saggar, Meenakshi Gupta, Harkirat Kaur
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 27-34
    » Abstract & References » doi: 10.5455/njppp.2013.3.27000
    Cited : 11 times [Click to see citing articles]

  • Pattern of mobile phone usage and its effects on psychological health, sleep, and academic performance in students of a medical university
    Naveenta Gupta, Sonia Garg, Khushdeep Arora
    Natl J Physiol Pharm Pharmacol. 2016; 6(2): 132-139
    » Abstract & References » doi: 10.5455/njppp.2016.6.0311201599
    Cited : 11 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimers disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 11 times [Click to see citing articles]

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 10 times [Click to see citing articles]

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114
    Cited : 7 times [Click to see citing articles]