E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313

Imam Adi Wicaksono, Dudi Runadi, Iman Firmansyah.

Abstract
Background: Acute bloody diarrhea, which is also called dysentery, is damaged of the intestinal mucosa, sepsis, and malnutrition. Shigella bacteria cause 50% of cases of dysentery; it is due to its ability to produce shiga toxin that can cause dysentery. In traditional medicine, dayak onions are commonly used as antibacterial agent to various infectious diseases.

Aims and Objectives: This study aims to determine the antibacterial activities of the ethanolic extract of dayak onions, determine the value of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extract against Shigella dysenteriae.

Materials and Methods: The study was conducted through several processes: (i) Extraction of dried dayak onions and phytochemical screening of extract, (ii) the antibacterial activity test of ethanolic extract of dayak onions, and (iii) determination value of MIC and MBC by tube dilution method.

Results: The result showed that ethanolic extract of dayak onions has antibacterial activity against S. dysenteriae bacteria. This extract has MIC and MBC in the concentration range of 12–14% (w/v). The antibacterial activity of this extract derived from alkaloids, monoterpenes and sesquiterpenes, steroids, flavonoids, polyphenols, and quinones.

Conclusion: The results of this research from the present investigation suggest that the extract of the studied plants can be used as potential leads to discover new drugs to control diarrhea infection.

Key words: Acute Bloody Diarrhea; Eleutherine palmifolia L. Merr.; Antibacterial Activity, Shigella dysenteriae


 
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Pubmed Style

Wicaksono IA, Runadi D, Firmansyah I. Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313. Natl J Physiol Pharm Pharmacol. 2018; 8(5): 741-744. doi:10.5455/njppp.2018.8.1248625012018


Web Style

Wicaksono IA, Runadi D, Firmansyah I. Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313. http://www.njppp.com/?mno=286328 [Access: October 15, 2018]. doi:10.5455/njppp.2018.8.1248625012018


AMA (American Medical Association) Style

Wicaksono IA, Runadi D, Firmansyah I. Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313. Natl J Physiol Pharm Pharmacol. 2018; 8(5): 741-744. doi:10.5455/njppp.2018.8.1248625012018



Vancouver/ICMJE Style

Wicaksono IA, Runadi D, Firmansyah I. Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313. Natl J Physiol Pharm Pharmacol. (2018), [cited October 15, 2018]; 8(5): 741-744. doi:10.5455/njppp.2018.8.1248625012018



Harvard Style

Wicaksono, I. A., Runadi, D. & Firmansyah, I. (2018) Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313. Natl J Physiol Pharm Pharmacol, 8 (5), 741-744. doi:10.5455/njppp.2018.8.1248625012018



Turabian Style

Wicaksono, Imam Adi, Dudi Runadi, and Iman Firmansyah. 2018. Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313. National Journal of Physiology, Pharmacy and Pharmacology, 8 (5), 741-744. doi:10.5455/njppp.2018.8.1248625012018



Chicago Style

Wicaksono, Imam Adi, Dudi Runadi, and Iman Firmansyah. "Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 741-744. doi:10.5455/njppp.2018.8.1248625012018



MLA (The Modern Language Association) Style

Wicaksono, Imam Adi, Dudi Runadi, and Iman Firmansyah. "Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313." National Journal of Physiology, Pharmacy and Pharmacology 8.5 (2018), 741-744. Print. doi:10.5455/njppp.2018.8.1248625012018



APA (American Psychological Association) Style

Wicaksono, I. A., Runadi, D. & Firmansyah, I. (2018) Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313. National Journal of Physiology, Pharmacy and Pharmacology, 8 (5), 741-744. doi:10.5455/njppp.2018.8.1248625012018





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