E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Drug utilization pattern and adverse drug reactions in patients on antidepressants

Tejashwini K, Aruna Bhushan, Suma S, Rajendrakumar Katte.

Abstract
Background: Depression is the most common mental illness, it is on the rise globally, and when patients do not follow prescribed antidepressant regimen or discontinue the therapy, it results in suboptimal treatment, relapse rate, and poor quality of life.

Aims and Objectives: The present study is designed to study the drug utilization pattern observed in patients receiving antidepressants in the psychiatry department and to study adverse drug reactions (ADR) observed in patients receiving antidepressants.

Materials and Methods: The study was conducted in the psychiatry department of BIMS hospital, Belagavi. 598 prescriptions with antidepressants were collected in a specially designed pro forma containing demographic, disease, and drug data. Moreover, during their follow–up, ADRs if any were noted. The data were analyzed statistically and the results were expressed as numbers and percentage.

Results: A total of 598 patients were analyzed. Among these, 57.86% were male and 42.13% were female. Most commonly affected age group and those who received maximum of the antidepressants were between 41 and 60 years. Fluoxetine (48.32%) was the most prescribed antidepressant. The total number of drugs prescribed was 957, with the average number of drugs per prescription being 1.60. In our study, 75.65% of drugs were prescribed by their generic name and the remaining 24.35% were brand names.

Conclusions: There is a need for drug utilization studies to encourage rational and appropriate use of drugs. Moreover, there is a growing concern to monitor and analyze the ADRs or any drug interactions to antidepressant drug pattern use. In this study, the use of antidepressants in patients was found to be appropriate.

Key words: Depression; Drug utilization study; Antidepressants


 
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Pubmed Style

K T, Bhushan A, S S, Katte R. Drug utilization pattern and adverse drug reactions in patients on antidepressants. Natl J Physiol Pharm Pharmacol. 2019; 9(1): 4-11. doi:10.5455/njppp.2019.9.103222910102018


Web Style

K T, Bhushan A, S S, Katte R. Drug utilization pattern and adverse drug reactions in patients on antidepressants. http://www.njppp.com/?mno=13744 [Access: March 25, 2019]. doi:10.5455/njppp.2019.9.103222910102018


AMA (American Medical Association) Style

K T, Bhushan A, S S, Katte R. Drug utilization pattern and adverse drug reactions in patients on antidepressants. Natl J Physiol Pharm Pharmacol. 2019; 9(1): 4-11. doi:10.5455/njppp.2019.9.103222910102018



Vancouver/ICMJE Style

K T, Bhushan A, S S, Katte R. Drug utilization pattern and adverse drug reactions in patients on antidepressants. Natl J Physiol Pharm Pharmacol. (2019), [cited March 25, 2019]; 9(1): 4-11. doi:10.5455/njppp.2019.9.103222910102018



Harvard Style

K, T., Bhushan, . A., S, . S. & Katte, . R. (2019) Drug utilization pattern and adverse drug reactions in patients on antidepressants. Natl J Physiol Pharm Pharmacol, 9 (1), 4-11. doi:10.5455/njppp.2019.9.103222910102018



Turabian Style

K, Tejashwini, Aruna Bhushan, Suma S, and Rajendrakumar Katte. 2019. Drug utilization pattern and adverse drug reactions in patients on antidepressants. National Journal of Physiology, Pharmacy and Pharmacology, 9 (1), 4-11. doi:10.5455/njppp.2019.9.103222910102018



Chicago Style

K, Tejashwini, Aruna Bhushan, Suma S, and Rajendrakumar Katte. "Drug utilization pattern and adverse drug reactions in patients on antidepressants." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 4-11. doi:10.5455/njppp.2019.9.103222910102018



MLA (The Modern Language Association) Style

K, Tejashwini, Aruna Bhushan, Suma S, and Rajendrakumar Katte. "Drug utilization pattern and adverse drug reactions in patients on antidepressants." National Journal of Physiology, Pharmacy and Pharmacology 9.1 (2019), 4-11. Print. doi:10.5455/njppp.2019.9.103222910102018



APA (American Psychological Association) Style

K, T., Bhushan, . A., S, . S. & Katte, . R. (2019) Drug utilization pattern and adverse drug reactions in patients on antidepressants. National Journal of Physiology, Pharmacy and Pharmacology, 9 (1), 4-11. doi:10.5455/njppp.2019.9.103222910102018





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