E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Effect of duration of hypertension on heart rate variability

Jyothi S, Mangala Gowri S R.

Abstract
Background: Hypertension is the most prevalent noncommunicable disease. It is a multisystem disorder that affects many organs of the body including cardiovascular system, and it markedly increases both morbidity and mortality in the population. Hypertension causes dysfunction of the cardiac autonomic nervous system leading to sympathovagal imbalance. Heart rate variability (HRV) is a non-invasive tool used to detect variation in RR intervals and has been proposed as early markers of vulnerability to ventricular arrhythmias. The present study was taken up to measure the effect of duration of the hypertension on HRV for early detection and early management of cardiac abnormalities.

Aims and Objectives: The objectives of the study were to evaluate the effect of duration of the hypertension on cardiac autonomic function in patients with primary hypertension by measuring HRV.

Materials and Methods: HRV test was performed on 50 male hypertensive patients who were divided into 2 groups, based on the duration of hypertension, i.e., duration of hypertension >5 years and <5 years. All the subjects were in between the age group of 41 and 60 years. Statistical analysis was done using unpaired t-test.

Results: Parameters of frequency-domain analysis of HRV such as low frequency (LF) (Hz), LF (ms2), and high frequency (nu) were significantly reduced in hypertensives with >5 years duration (P < 0.01). Time domain parameters such as root mean square successive differences, triangular interpolation of normal to normal, and percentage of differences between adjacent normal RR interval 50% were reduced in hypertensive subjects with duration >5 years, and it was highly significant. P < 0.001 showing decreased in parasympathetic activity in long-standing hypertension.

Conclusion: Study showed reduced HRV parameters showing decreased parasympathetic activity in long-standing hypertension leading to an imbalance in cardiac autonomic function. It is very much important to evaluate the cardiac autonomic function status in long-standing hypertension using simple non-invasive tools for early detection and treatment of cardiac arrhythmias and other variations in cardiac function status.

Key words: Hypertension; Time Domain Parameters; Frequency Domain Parameters


 
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Pubmed Style

S J, R MGS. Effect of duration of hypertension on heart rate variability. Natl J Physiol Pharm Pharmacol. 2019; 9(1): 95-98. doi:10.5455/njppp.2019.9.1031017102018


Web Style

S J, R MGS. Effect of duration of hypertension on heart rate variability. http://www.njppp.com/?mno=11360 [Access: March 25, 2019]. doi:10.5455/njppp.2019.9.1031017102018


AMA (American Medical Association) Style

S J, R MGS. Effect of duration of hypertension on heart rate variability. Natl J Physiol Pharm Pharmacol. 2019; 9(1): 95-98. doi:10.5455/njppp.2019.9.1031017102018



Vancouver/ICMJE Style

S J, R MGS. Effect of duration of hypertension on heart rate variability. Natl J Physiol Pharm Pharmacol. (2019), [cited March 25, 2019]; 9(1): 95-98. doi:10.5455/njppp.2019.9.1031017102018



Harvard Style

S, J. & R, . M. G. S. (2019) Effect of duration of hypertension on heart rate variability. Natl J Physiol Pharm Pharmacol, 9 (1), 95-98. doi:10.5455/njppp.2019.9.1031017102018



Turabian Style

S, Jyothi, and Mangala Gowri S R. 2019. Effect of duration of hypertension on heart rate variability. National Journal of Physiology, Pharmacy and Pharmacology, 9 (1), 95-98. doi:10.5455/njppp.2019.9.1031017102018



Chicago Style

S, Jyothi, and Mangala Gowri S R. "Effect of duration of hypertension on heart rate variability." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 95-98. doi:10.5455/njppp.2019.9.1031017102018



MLA (The Modern Language Association) Style

S, Jyothi, and Mangala Gowri S R. "Effect of duration of hypertension on heart rate variability." National Journal of Physiology, Pharmacy and Pharmacology 9.1 (2019), 95-98. Print. doi:10.5455/njppp.2019.9.1031017102018



APA (American Psychological Association) Style

S, J. & R, . M. G. S. (2019) Effect of duration of hypertension on heart rate variability. National Journal of Physiology, Pharmacy and Pharmacology, 9 (1), 95-98. doi:10.5455/njppp.2019.9.1031017102018





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