Abstract
Background: The septal region has attracted the attention of many due to its apparent involvement in variety of motivational, emotional, and associate process.

Aims and Objectives: This study was done to assess the effect of the septal lesion on sexual behavior in male albino rats.

Materials and Methods: In this experimental study, 16 sexually experienced male albino rats were selected randomly out of which 8 rats were septal lesioned (participants) and remaining 8 rats were shamoperated (control). To assess the effect of septal lesion, we compared the latencies and frequencies of male sexual behavior components (pursuit, mount, intromission, and ejaculation) in sham and septal lesion rats. The occurrence of each pursuit, mount, intromission, and ejaculation was scored according to classical criteria.

Results: Compared to sham-lesioned, the sexual behavior is significantly reduced in septal lesioned rats as indicated by an increase in latencies of different components and shows a significant decrease in intromission and ejaculation frequency, decrease in sex drive but no change in pursuit and mount frequency.

Conclusion: The result indicates that the sexual behavior is modulated in bilateral septal lesioned male rats which proves the role of septal nuclei in controlling the reproductive functions in male rats.

Key words: Bilateral Septal Nuclei Lesion; Sham Lesion; Young Male Rats; Sexual Behavior