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Original Research Open Access


Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes

Leya Elizabeth Babu, Anuradha Joshi.

Abstract
Background: The prevalence of diabetes is rapidly rising all over the globe at an alarming rate. Complications of diabetes include microvascular and macrovascular complications. High-Sensitivity C-reactive protein (hs-CRP) is an acute phase reactant and a sensitive marker of inflammation. In addition to traditional cardiovascular risk factors, elevation in hs-CRP can be used to predict increased cardiovascular risk in diabetic patients.

Aims and Objectives: This study was planned to estimate hs-CRP and fasting blood glucose (FBG) levels in diabetic and non-diabetic participants and to find out if there is any correlation between blood glucose and hs-CRP levels in diabetic and non-diabetic participants.

Materials and Methods: In this study, hs-CRP and FBG levels of 120 participants were estimated. Among which 60 were diabetic, and 60 were non-diabetic participants. Participants were chosen based on inclusion and exclusion criteria. FBG was estimated by glucose oxidase peroxidase method and hs-CRP was estimated chemiluminescence immunoassay method. Data analysis were analyzed by unpaired t-test using Statistical Package for the Social Sciences Version 19.0.

Results: The results of this study showed that hs-CRP increased as FBG increased. There was positive correlation seen between hs-CRP and blood glucose levels in both study and control group. Hs-CRP was seen to be much higher in diabetic participants than in non-diabetic participants.

Conclusion: Thus proving that hyperglycemia itself is a factor that can cause increase of serum hs-CRP levels in Type 2 diabetic participants.

Key words: Diabetes Mellitus; Fasting Blood Glucose; High-sensitivity C-reactive Protein


 
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How to Cite this Article
Pubmed Style

Babu LE, Joshi A. Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes. Natl J Physiol Pharm Pharmacol. 2018; 8(1): 37-41. doi:10.5455/njppp.2018.8.0726805082017


Web Style

Babu LE, Joshi A. Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes. http://www.njppp.com/?mno=269312 [Access: January 23, 2018]. doi:10.5455/njppp.2018.8.0726805082017


AMA (American Medical Association) Style

Babu LE, Joshi A. Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes. Natl J Physiol Pharm Pharmacol. 2018; 8(1): 37-41. doi:10.5455/njppp.2018.8.0726805082017



Vancouver/ICMJE Style

Babu LE, Joshi A. Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes. Natl J Physiol Pharm Pharmacol. (2018), [cited January 23, 2018]; 8(1): 37-41. doi:10.5455/njppp.2018.8.0726805082017



Harvard Style

Babu, L. E. & Joshi, A. (2018) Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes. Natl J Physiol Pharm Pharmacol, 8 (1), 37-41. doi:10.5455/njppp.2018.8.0726805082017



Turabian Style

Babu, Leya Elizabeth, and Anuradha Joshi. 2018. Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes. National Journal of Physiology, Pharmacy and Pharmacology, 8 (1), 37-41. doi:10.5455/njppp.2018.8.0726805082017



Chicago Style

Babu, Leya Elizabeth, and Anuradha Joshi. "Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 37-41. doi:10.5455/njppp.2018.8.0726805082017



MLA (The Modern Language Association) Style

Babu, Leya Elizabeth, and Anuradha Joshi. "Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes." National Journal of Physiology, Pharmacy and Pharmacology 8.1 (2018), 37-41. Print. doi:10.5455/njppp.2018.8.0726805082017



APA (American Psychological Association) Style

Babu, L. E. & Joshi, A. (2018) Correlation of high-sensitivity C-reactive protein with blood sugar level in patients with Type 2 diabetes. National Journal of Physiology, Pharmacy and Pharmacology, 8 (1), 37-41. doi:10.5455/njppp.2018.8.0726805082017



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