E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Electrocardiographic changes in subclinical hypothyroidism

Vishalaxi Jadhav, Khararashah F Kammar.

Abstract
Background: Subclinical hypothyroidism (SCH) is an apparently asymptomatic condition defined by increased serum thyrotropin (thyroid-stimulating hormone) concentrations, but normal serum free T3 and free T4 hormone levels. Thyroid hormones are known to affect the heart and vasculature. The effect of SCH on cardiovascular system is not much studied.

Aims and Objectives: The objectives of this study were to study the electrocardiogram (ECG) changes in a group of newly diagnosed subclinical hypothyroid females and to compare the ECG changes in subclinical hypothyroid females with normal healthy euthyroid individuals.

Materials and Methods: We studied 30 non-pregnant females with primary SCH in the age group of 20–40 years, who were newly diagnosed and untreated. Thirty age- and body mass index-matched healthy individuals were taken as controls. Clinical and biochemical parameters and ECG were studied. Statistical software, “GraphPad QuickCalcs,” was used for the statistical analysis.

Results: Mean QTc interval of the study group was significantly longer than those of the control group (P = 0.037). Other parameters of ECG were comparable in both the groups.

Conclusion: ECG changes in SCH showed increase in the QTc interval as compared to controls, which predisposes to the potentially life-threatening ventricular arrhythmias. However, the other parameters of ECG such as QRS interval, PR interval, and QRS axis were similar to the controls.

Key words: Subclinical Hypothyroidism; Thyroid Hormones; Electrocardiogram; QTc Interval


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Vishalaxi Jadhav
Articles by Khararashah F Kammar
on Google
on Google Scholar
Article Statistics
 Viewed: 1
Downloaded: 15


How to Cite this Article
Pubmed Style

Jadhav V, Kammar KF. Electrocardiographic changes in subclinical hypothyroidism. doi:10.5455/njppp.2020.10.03077202003042020


Web Style

Jadhav V, Kammar KF. Electrocardiographic changes in subclinical hypothyroidism. http://www.njppp.com/?mno=94246 [Access: April 19, 2020]. doi:10.5455/njppp.2020.10.03077202003042020


AMA (American Medical Association) Style

Jadhav V, Kammar KF. Electrocardiographic changes in subclinical hypothyroidism. doi:10.5455/njppp.2020.10.03077202003042020



Vancouver/ICMJE Style

Jadhav V, Kammar KF. Electrocardiographic changes in subclinical hypothyroidism. doi:10.5455/njppp.2020.10.03077202003042020



Harvard Style

Jadhav, V. & Kammar, . K. F. (2020) Electrocardiographic changes in subclinical hypothyroidism. doi:10.5455/njppp.2020.10.03077202003042020



Turabian Style

Jadhav, Vishalaxi, and Khararashah F Kammar. 2020. Electrocardiographic changes in subclinical hypothyroidism. doi:10.5455/njppp.2020.10.03077202003042020



Chicago Style

Jadhav, Vishalaxi, and Khararashah F Kammar. "Electrocardiographic changes in subclinical hypothyroidism." doi:10.5455/njppp.2020.10.03077202003042020



MLA (The Modern Language Association) Style

Jadhav, Vishalaxi, and Khararashah F Kammar. "Electrocardiographic changes in subclinical hypothyroidism." doi:10.5455/njppp.2020.10.03077202003042020



APA (American Psychological Association) Style

Jadhav, V. & Kammar, . K. F. (2020) Electrocardiographic changes in subclinical hypothyroidism. doi:10.5455/njppp.2020.10.03077202003042020





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Evaluation of potential drug-drug interaction in indoor patients of pediatric department of tertiary care hospital
    Simran Patel, Mayur Chaudhari, Nrupal Patel
    Natl J Physiol Pharm Pharmacol. 2019; 9(10): 1012-1016
    » Abstract » doi: 10.5455/njppp.2019.9.0725209072019

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Most Cited Articles
  • Promoting active learning in respiratory physiology – Positive student perception and improved outcomes
    Richa Thaman, Sukhjinder Dhillon, Sanjeev Saggar, Meenakshi Gupta, Harkirat Kaur
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 27-34
    » Abstract & References » doi: 10.5455/njppp.2013.3.27000
    Cited : 11 times [Click to see citing articles]

  • Pattern of mobile phone usage and its effects on psychological health, sleep, and academic performance in students of a medical university
    Naveenta Gupta, Sonia Garg, Khushdeep Arora
    Natl J Physiol Pharm Pharmacol. 2016; 6(2): 132-139
    » Abstract & References » doi: 10.5455/njppp.2016.6.0311201599
    Cited : 11 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimer’s disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 11 times [Click to see citing articles]

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 10 times [Click to see citing articles]

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114
    Cited : 7 times [Click to see citing articles]