E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Impact on the hematopoietic system by alcoholism and the influence of duration of consumption

Sarah Varghese, Mudanna G Bandelkar, Jnaneshwara P Shenoy, Shivakumar Jagadeesan.

Abstract
Background: The abuse of alcohol brings with it untold misery in the form of health-related problems as well as social issues. Chronic misuse of alcohol affects literally every aspect of bodily functions and organ systems functioning.

Aims and Objectives: This study’s aim was to observe the effect of alcoholism on select blood parameters.

Materials and Methods: A total of 50 subjects who met the criteria for alcoholism and other prescribed inclusion criteria, and 50 age- and sex-matched controls formed the study population. Random blood samples obtained from patients as well as controls were used to estimate complete blood count (hemoglobin [Hb], red blood corpuscle (RBC) count, total leukocyte count (TLC), packed cell volume (PCV), mean corpuscular volume (MCV), and platelet count). Duration of alcohol consumption was also noted. Correlational analysis and t-test were the statistical tests adopted.

Results: There were significantly reduced values for Hb, RBC count, PCV, and platelet count in alcoholics, and a significant increase in MCV in the same group compared to controls. TLC numbers were similar in both groups, and except for PCV, no other parameters showed any significant correlation with the duration of alcohol consumption.

Conclusion: Excessive alcohol consumption affects the erythrocytes and thrombocytes while showing no effect on the leukocytes. In general, duration of alcohol consumption does not seem to influence the severity of these changes.

Key words: Alcoholism; Hemoglobin; Leukocytes; Mean Corpuscular Volume; Platelets


 
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Pubmed Style

Varghese S, Bandelkar MG, Shenoy JP, Jagadeesan S. Impact on the hematopoietic system by alcoholism and the influence of duration of consumption. Natl J Physiol Pharm Pharmacol. 2019; 9(8): 742-745. doi:10.5455/njppp.2019.9.0518118052019


Web Style

Varghese S, Bandelkar MG, Shenoy JP, Jagadeesan S. Impact on the hematopoietic system by alcoholism and the influence of duration of consumption. http://www.njppp.com/?mno=49070 [Access: August 23, 2019]. doi:10.5455/njppp.2019.9.0518118052019


AMA (American Medical Association) Style

Varghese S, Bandelkar MG, Shenoy JP, Jagadeesan S. Impact on the hematopoietic system by alcoholism and the influence of duration of consumption. Natl J Physiol Pharm Pharmacol. 2019; 9(8): 742-745. doi:10.5455/njppp.2019.9.0518118052019



Vancouver/ICMJE Style

Varghese S, Bandelkar MG, Shenoy JP, Jagadeesan S. Impact on the hematopoietic system by alcoholism and the influence of duration of consumption. Natl J Physiol Pharm Pharmacol. (2019), [cited August 23, 2019]; 9(8): 742-745. doi:10.5455/njppp.2019.9.0518118052019



Harvard Style

Varghese, S., Bandelkar, . M. G., Shenoy, . J. P. & Jagadeesan, . S. (2019) Impact on the hematopoietic system by alcoholism and the influence of duration of consumption. Natl J Physiol Pharm Pharmacol, 9 (8), 742-745. doi:10.5455/njppp.2019.9.0518118052019



Turabian Style

Varghese, Sarah, Mudanna G Bandelkar, Jnaneshwara P Shenoy, and Shivakumar Jagadeesan. 2019. Impact on the hematopoietic system by alcoholism and the influence of duration of consumption. National Journal of Physiology, Pharmacy and Pharmacology, 9 (8), 742-745. doi:10.5455/njppp.2019.9.0518118052019



Chicago Style

Varghese, Sarah, Mudanna G Bandelkar, Jnaneshwara P Shenoy, and Shivakumar Jagadeesan. "Impact on the hematopoietic system by alcoholism and the influence of duration of consumption." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 742-745. doi:10.5455/njppp.2019.9.0518118052019



MLA (The Modern Language Association) Style

Varghese, Sarah, Mudanna G Bandelkar, Jnaneshwara P Shenoy, and Shivakumar Jagadeesan. "Impact on the hematopoietic system by alcoholism and the influence of duration of consumption." National Journal of Physiology, Pharmacy and Pharmacology 9.8 (2019), 742-745. Print. doi:10.5455/njppp.2019.9.0518118052019



APA (American Psychological Association) Style

Varghese, S., Bandelkar, . M. G., Shenoy, . J. P. & Jagadeesan, . S. (2019) Impact on the hematopoietic system by alcoholism and the influence of duration of consumption. National Journal of Physiology, Pharmacy and Pharmacology, 9 (8), 742-745. doi:10.5455/njppp.2019.9.0518118052019





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