E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Improvement in quality of life with buprenorphine in opioid dependence

Abhinav Kapoor, Kanchan Kohli, Abhishek Kapoor, Nimmi A Jose.

Abstract
Background: The excessive opioid abuse leads to impaired quality of life (QOL) in opioid abusers. The data on the effect of opioid substitution therapy (OST) on the QOL of opioid dependent are lacking from India.

Aims and Objectives: This study aims to check the effect of OST on QOL of opioid abuser in Gurgaon for 6-month follow-up.

Materials and Methods: A total of 202 patients with opioid dependent were taken for the study from a deaddiction center in Gurgaon. They received sublingual buprenorphine as oral substitution therapy and were assessed with Opioid Treatment Index (OTI) and Severity of Dependence Scale, at baseline, 1 month, 3rd month, and 6th month. Patients were also assessed with the World Health Organization QOL (WHOQOL) scale (Hindi version) at baseline, 3rd month, and 6th month to assess the improvement in QOL.

Results: The significant improvement has been seen in OTI in opioid abuser 1 month onward and with regard to the WHOQOL-BREF scale scores, statistically significant P value has found for domain 2 (psychological) and domain 3 (social relationship) at 3rd and 6 months in heroin abuser.

Conclusion: Improvement in QOL was seen with buprenorphine in patients of opioid dependence in Gurgaon.

Key words: Opioid; World Health Organization Quality of Life; Buprenorphine; Opioid Treatment Index


 
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Pubmed Style

Kapoor A, Kohli K, Kapoor A, Jose NA. Improvement in quality of life with buprenorphine in opioid dependence. Natl J Physiol Pharm Pharmacol. 2019; 9(7): 689-694. doi:10.5455/njppp.2019.9.0419224052019


Web Style

Kapoor A, Kohli K, Kapoor A, Jose NA. Improvement in quality of life with buprenorphine in opioid dependence. http://www.njppp.com/?mno=46085 [Access: October 18, 2019]. doi:10.5455/njppp.2019.9.0419224052019


AMA (American Medical Association) Style

Kapoor A, Kohli K, Kapoor A, Jose NA. Improvement in quality of life with buprenorphine in opioid dependence. Natl J Physiol Pharm Pharmacol. 2019; 9(7): 689-694. doi:10.5455/njppp.2019.9.0419224052019



Vancouver/ICMJE Style

Kapoor A, Kohli K, Kapoor A, Jose NA. Improvement in quality of life with buprenorphine in opioid dependence. Natl J Physiol Pharm Pharmacol. (2019), [cited October 18, 2019]; 9(7): 689-694. doi:10.5455/njppp.2019.9.0419224052019



Harvard Style

Kapoor, A., Kohli, . K., Kapoor, . A. & Jose, . N. A. (2019) Improvement in quality of life with buprenorphine in opioid dependence. Natl J Physiol Pharm Pharmacol, 9 (7), 689-694. doi:10.5455/njppp.2019.9.0419224052019



Turabian Style

Kapoor, Abhinav, Kanchan Kohli, Abhishek Kapoor, and Nimmi A Jose. 2019. Improvement in quality of life with buprenorphine in opioid dependence. National Journal of Physiology, Pharmacy and Pharmacology, 9 (7), 689-694. doi:10.5455/njppp.2019.9.0419224052019



Chicago Style

Kapoor, Abhinav, Kanchan Kohli, Abhishek Kapoor, and Nimmi A Jose. "Improvement in quality of life with buprenorphine in opioid dependence." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 689-694. doi:10.5455/njppp.2019.9.0419224052019



MLA (The Modern Language Association) Style

Kapoor, Abhinav, Kanchan Kohli, Abhishek Kapoor, and Nimmi A Jose. "Improvement in quality of life with buprenorphine in opioid dependence." National Journal of Physiology, Pharmacy and Pharmacology 9.7 (2019), 689-694. Print. doi:10.5455/njppp.2019.9.0419224052019



APA (American Psychological Association) Style

Kapoor, A., Kohli, . K., Kapoor, . A. & Jose, . N. A. (2019) Improvement in quality of life with buprenorphine in opioid dependence. National Journal of Physiology, Pharmacy and Pharmacology, 9 (7), 689-694. doi:10.5455/njppp.2019.9.0419224052019





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