E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital

Aashal Shah, Richa Verma, Preeti Yadav, Jayshree Patel.

Abstract
Background: Prescribing pattern of antipsychotics has changed over the decade with availability of newer antipsychotics.

Aims and Objectives: This study aims to analyze the utilization pattern of antipsychotics at our hospital.

Materials and Methods: A retrospective study of case files of patients receiving antipsychotics was carried out in the psychiatry outpatient department of new civil hospital, Surat, for a period of 6 months. Pattern of antipsychotic prescription, the World Health Organization (WHO) prescribing indicators, defined daily dose (DDD)/1000 inhabitants/day (DID), prescribed daily dose (PDD), and the PDD-to-DDD ratio were assessed.

Results: A total of 2115 drugs were prescribed in 631 prescriptions, of which 804 (38.01%) were antipsychotics. Schizophrenia (55.31%) was the most common diagnosis. Sedative-hypnotics (30.23%) were the most common coprescribed drug group. Atypical antipsychotics were more commonly prescribed – olanzapine: 47.39%, risperidone: 27.49%, clozapine: 13.06%, and others: 12.06%. The average number of antipsychotics/prescription: 1.29 ± 0.53; prescribing of antipsychotics by generic name: 95.02%; prescribing from the WHO essential medicines list: 43.66%; prescribing from National List of Essential Medicines: 47.89%; prescribing for injections of antipsychotics: 0.62%; prescriptions of fixed-drug combinations: 0.50%, and DID of antipsychotics: 0.014 mg. PDD-to-DDD ratios for trifluoperazine, ziprasidone, amisulpride, and clozapine were <1, while for risperidone and haloperidol, it was =1 and for olanzapine and aripiprazole, it was >1.

Conclusion: The second‑generation antipsychotic olanzapine was the most commonly prescribed antipsychotic. The prescriptions were complete and followed principles of rational prescribing in majority of cases. Prescribing the drugs available from hospital supply will decrease cost of therapy in chronic psychiatric disorders.

Key words: Anatomical Therapeutic Chemical-Defined Daily Dose; Olanzapine; Antipsychotic Agents


 
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How to Cite this Article
Pubmed Style

Shah A, Verma R, Yadav P, Patel J, . Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital. Natl J Physiol Pharm Pharmacol. 2019; 9(11): 1111-1116. doi:10.5455/njppp.2019.9.0413123082019


Web Style

Shah A, Verma R, Yadav P, Patel J, . Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital. http://www.njppp.com/?mno=42201 [Access: February 15, 2020]. doi:10.5455/njppp.2019.9.0413123082019


AMA (American Medical Association) Style

Shah A, Verma R, Yadav P, Patel J, . Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital. Natl J Physiol Pharm Pharmacol. 2019; 9(11): 1111-1116. doi:10.5455/njppp.2019.9.0413123082019



Vancouver/ICMJE Style

Shah A, Verma R, Yadav P, Patel J, . Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital. Natl J Physiol Pharm Pharmacol. (2019), [cited February 15, 2020]; 9(11): 1111-1116. doi:10.5455/njppp.2019.9.0413123082019



Harvard Style

Shah, A. . ., Verma, R., Yadav, P. . ., Patel, J. . & (2019) Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital. Natl J Physiol Pharm Pharmacol, 9 (11), 1111-1116. doi:10.5455/njppp.2019.9.0413123082019



Turabian Style

Shah, Aashal , Richa Verma, Preeti Yadav, Jayshree Patel, and . 2019. Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital. National Journal of Physiology, Pharmacy and Pharmacology, 9 (11), 1111-1116. doi:10.5455/njppp.2019.9.0413123082019



Chicago Style

Shah, Aashal , Richa Verma, Preeti Yadav, Jayshree Patel, and . "Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 1111-1116. doi:10.5455/njppp.2019.9.0413123082019



MLA (The Modern Language Association) Style

Shah, Aashal , Richa Verma, Preeti Yadav, Jayshree Patel, and . "Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital." National Journal of Physiology, Pharmacy and Pharmacology 9.11 (2019), 1111-1116. Print. doi:10.5455/njppp.2019.9.0413123082019



APA (American Psychological Association) Style

Shah, A. . ., Verma, R., Yadav, P. . ., Patel, J. . & (2019) Drug utilization study of antipsychotic drugs in the psychiatry outpatient department of a tertiary care hospital. National Journal of Physiology, Pharmacy and Pharmacology, 9 (11), 1111-1116. doi:10.5455/njppp.2019.9.0413123082019





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