E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


A prospective observational study on usage of inotropes in a coronary care unit

Dr. B. Arumugam , Dr. Y. Nisha Maheswari , Dr. B.Meenakshi , Dr. J.Ezhil Ramya , Dr. A.S.Arul .

Abstract
Background: Treatment with inotropes is generally reserved for most severely ill patients and so increased mortality can be coincidental. Several clinical trials in a wide range of clinical settings have been performed with controversial results to determine the effects of inotropes on mortality. Hence, the present study was done to evaluate the effect of inotropes and vasopressors used in our setting on the outcome of the patients.

Aims and Objectives: This study aims to assess the clinical profile of patients requiring inotropes and their outcomes in a coronary care unit.

Materials and Methods: This prospective, observational, hospital-based study was conducted in intensive coronary care unit (ICCU). Detailed history and findings on clinical examination were recorded. Inotropes used, indication, duration of stay in hospital, various complications, and outcomes were also entered. Patients were monitored daily until their discharge or death.

Results: The total number of patients admitted in ICCU during the study period was 199, of which 25 (12.6%) patients needed inotropes. The most common risk factor for inotrope use was diabetes mellitus (40%). The most common inotrope used was noradrenaline. The average duration of hospital stay for patients requiring inotropes was 4.7 days. Of 25 patients requiring inotropes, 64% (n = 16) survived and 36% (n = 9) expired. Chi-square test revealed that the need of inotropes was significantly associated with increased risk of death.

Conclusion: In the coronary care unit, the use of inotropes was associated with poor outcomes. Inotropes may not be detrimental per se, but accurate benefits and risks and selection of the correct agent are required in every clinical setting.

Key words: Inotropes; Intensive Coronary Care Unit; Clinical Profile; Outcome; Mortality


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Dr. B. Arumugam
Articles by Dr. Y. Nisha Maheswari
Articles by Dr. B.Meenakshi
Articles by Dr. J.Ezhil Ramya
Articles by Dr. A.S.Arul
on Google
on Google Scholar
Article Statistics
 Viewed: 1373
Downloaded: 82


How to Cite this Article
Pubmed Style

DBA, , DB, DJR, DA, . A prospective observational study on usage of inotropes in a coronary care unit. Natl J Physiol Pharm Pharmacol. 2019; 9(12): 1239-1245. doi:10.5455/njppp.2019.9.0413710102019


Web Style

DBA, , DB, DJR, DA, . A prospective observational study on usage of inotropes in a coronary care unit. http://www.njppp.com/?mno=39836 [Access: February 15, 2020]. doi:10.5455/njppp.2019.9.0413710102019


AMA (American Medical Association) Style

DBA, , DB, DJR, DA, . A prospective observational study on usage of inotropes in a coronary care unit. Natl J Physiol Pharm Pharmacol. 2019; 9(12): 1239-1245. doi:10.5455/njppp.2019.9.0413710102019



Vancouver/ICMJE Style

DBA, , DB, DJR, DA, . A prospective observational study on usage of inotropes in a coronary care unit. Natl J Physiol Pharm Pharmacol. (2019), [cited February 15, 2020]; 9(12): 1239-1245. doi:10.5455/njppp.2019.9.0413710102019



Harvard Style

, D. B. A. . ., , , D. B. . ., , D. J. R. . ., , D. A. . . & (2019) A prospective observational study on usage of inotropes in a coronary care unit. Natl J Physiol Pharm Pharmacol, 9 (12), 1239-1245. doi:10.5455/njppp.2019.9.0413710102019



Turabian Style

, Dr. B. Arumugam , Dr. Y. Nisha Maheswari, Dr. B.Meenakshi, Dr. J.Ezhil Ramya, Dr. A.S.Arul, and . 2019. A prospective observational study on usage of inotropes in a coronary care unit. National Journal of Physiology, Pharmacy and Pharmacology, 9 (12), 1239-1245. doi:10.5455/njppp.2019.9.0413710102019



Chicago Style

, Dr. B. Arumugam , Dr. Y. Nisha Maheswari, Dr. B.Meenakshi, Dr. J.Ezhil Ramya, Dr. A.S.Arul, and . "A prospective observational study on usage of inotropes in a coronary care unit." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 1239-1245. doi:10.5455/njppp.2019.9.0413710102019



MLA (The Modern Language Association) Style

, Dr. B. Arumugam , Dr. Y. Nisha Maheswari, Dr. B.Meenakshi, Dr. J.Ezhil Ramya, Dr. A.S.Arul, and . "A prospective observational study on usage of inotropes in a coronary care unit." National Journal of Physiology, Pharmacy and Pharmacology 9.12 (2019), 1239-1245. Print. doi:10.5455/njppp.2019.9.0413710102019



APA (American Psychological Association) Style

, D. B. A. . ., , , D. B. . ., , D. J. R. . ., , D. A. . . & (2019) A prospective observational study on usage of inotropes in a coronary care unit. National Journal of Physiology, Pharmacy and Pharmacology, 9 (12), 1239-1245. doi:10.5455/njppp.2019.9.0413710102019





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Evaluation of potential drug-drug interaction in indoor patients of pediatric department of tertiary care hospital
    Simran Patel, Mayur Chaudhari, Nrupal Patel
    Natl J Physiol Pharm Pharmacol. 2019; 9(10): 1012-1016
    » Abstract » doi: 10.5455/njppp.2019.9.0725209072019

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Most Cited Articles
  • Promoting active learning in respiratory physiology – Positive student perception and improved outcomes
    Richa Thaman, Sukhjinder Dhillon, Sanjeev Saggar, Meenakshi Gupta, Harkirat Kaur
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 27-34
    » Abstract & References » doi: 10.5455/njppp.2013.3.27000
    Cited : 11 times [Click to see citing articles]

  • Pattern of mobile phone usage and its effects on psychological health, sleep, and academic performance in students of a medical university
    Naveenta Gupta, Sonia Garg, Khushdeep Arora
    Natl J Physiol Pharm Pharmacol. 2016; 6(2): 132-139
    » Abstract & References » doi: 10.5455/njppp.2016.6.0311201599
    Cited : 11 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimer’s disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 11 times [Click to see citing articles]

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 10 times [Click to see citing articles]

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114
    Cited : 7 times [Click to see citing articles]