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Original Research 


High-resolution manometric features of achalasia of the cardia

Deepanjan Dey, Karuna Datta, DK Dubey, Deep Sharma.

Abstract
Background: Achalasia of the cardia is a common esophageal motility disorder. High-resolution manometry is the gold standard for the diagnosis of achalasia. The body of the esophagus and the lower esophageal sphincter (LOS) exhibits various motility characteristics that are typical to achalasia.

Aims and Objectives: The study was conducted to study the physiology of the LOS in achalasia with a 16-channel water perfusion high-resolution esophageal manometer.

Materials and Methods: High-resolution esophageal manometry was performed in 13 adult patients of achalasia and the functional patterns were evaluated.

Results: 12 of 13 cases of achalasia had a high basal LOS pressure (BLOSP), while one had reduced pressure. All cases of achalasia had an elevated LOS nadir pressure, indicating an incomplete relaxation of the LOS. All 13 cases of achalasia showed the absence of peristalsis.

Conclusion: A reduced BLOSP is rare in achalasia and so is a normal BLOSP; however, they have been described in literature, and hence, the BLOSP as such cannot be considered as a diagnostic feature of achalasia on manometry.

Key words: Achalasia; High-Resolution Manometry; Lower Esophageal Sphincter; Lower Esophageal Sphincter Relaxation


 
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Pubmed Style

Dey D, Datta K, Dubey D, Sharma D. High-resolution manometric features of achalasia of the cardia. Natl J Physiol Pharm Pharmacol. 2018; 8(12): 1591-1594. doi:10.5455/njppp.2018.8.0412707092018


Web Style

Dey D, Datta K, Dubey D, Sharma D. High-resolution manometric features of achalasia of the cardia. http://www.njppp.com/?mno=296634 [Access: December 13, 2018]. doi:10.5455/njppp.2018.8.0412707092018


AMA (American Medical Association) Style

Dey D, Datta K, Dubey D, Sharma D. High-resolution manometric features of achalasia of the cardia. Natl J Physiol Pharm Pharmacol. 2018; 8(12): 1591-1594. doi:10.5455/njppp.2018.8.0412707092018



Vancouver/ICMJE Style

Dey D, Datta K, Dubey D, Sharma D. High-resolution manometric features of achalasia of the cardia. Natl J Physiol Pharm Pharmacol. (2018), [cited December 13, 2018]; 8(12): 1591-1594. doi:10.5455/njppp.2018.8.0412707092018



Harvard Style

Dey, D., Datta, . K., Dubey, . D. & Sharma, . D. (2018) High-resolution manometric features of achalasia of the cardia. Natl J Physiol Pharm Pharmacol, 8 (12), 1591-1594. doi:10.5455/njppp.2018.8.0412707092018



Turabian Style

Dey, Deepanjan, Karuna Datta, DK Dubey, and Deep Sharma. 2018. High-resolution manometric features of achalasia of the cardia. National Journal of Physiology, Pharmacy and Pharmacology, 8 (12), 1591-1594. doi:10.5455/njppp.2018.8.0412707092018



Chicago Style

Dey, Deepanjan, Karuna Datta, DK Dubey, and Deep Sharma. "High-resolution manometric features of achalasia of the cardia." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 1591-1594. doi:10.5455/njppp.2018.8.0412707092018



MLA (The Modern Language Association) Style

Dey, Deepanjan, Karuna Datta, DK Dubey, and Deep Sharma. "High-resolution manometric features of achalasia of the cardia." National Journal of Physiology, Pharmacy and Pharmacology 8.12 (2018), 1591-1594. Print. doi:10.5455/njppp.2018.8.0412707092018



APA (American Psychological Association) Style

Dey, D., Datta, . K., Dubey, . D. & Sharma, . D. (2018) High-resolution manometric features of achalasia of the cardia. National Journal of Physiology, Pharmacy and Pharmacology, 8 (12), 1591-1594. doi:10.5455/njppp.2018.8.0412707092018





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