E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis

Darakhshan Rizvi, Afroz Abidi, Syed Mohd Faiz, Roohana Hasan, Anupriya Thadani.

Abstract
Background: Oral submucous fibrosis (OSMF) is a chronic condition which has characteristics of inflammation and fibrosis in the oral cavity which is progressive in nature. Steroids are the standard treatment of OSMF, but considering their side effect profile, we thought of taking herbal preparations as these have minimal side effects.

Aims and Objectives: This study aims to compare the efficacy of curcumin and tulsi gels in OSMF.

Materials and Methods: This is a prospective, randomized study conducted in ENT OPD on 60 patients who were diagnosed on the the basis of clinical criteria of OSMF. Patients were divided into two groups, one group was given tulsi gel and other group curcumin gel and each group was given topical steroids along with the test drugs. Follow-up was done for 6 weeks and patients were assessed on the basis of improvement in interincisal distance, burning sensation, and tongue protrusion at 2, 4, and 6 weeks.

Results: There was an improvement in all the three parameters at subsequent visits, but the curcumin gel showed better improvement than tulsi gel in burning sensation after 6 weeks of treatment which was highly statistically significant P < 0.01.

Conclusion: Curcumin gel and tulsi gel are effective in improving OSMF symptoms, but curcumin gel is more efficacious without any side effects. Hence, we can advocate these drugs as adjuvant treatment in addition to the recommended treatment.

Key words: Curcumin Gel; Tulsi Gel; Burning Sensation; Interincisal Distance; Oral Submucous Fibrosis


 
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Pubmed Style

Rizvi D, Abidi A, Faiz SM, Hasan R, Thadani A. Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis. Natl J Physiol Pharm Pharmacol. 2019; 9(4): 343-348. doi:10.5455/njppp.2019.9.0203416022019


Web Style

Rizvi D, Abidi A, Faiz SM, Hasan R, Thadani A. Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis. http://www.njppp.com/?mno=29307 [Access: July 22, 2019]. doi:10.5455/njppp.2019.9.0203416022019


AMA (American Medical Association) Style

Rizvi D, Abidi A, Faiz SM, Hasan R, Thadani A. Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis. Natl J Physiol Pharm Pharmacol. 2019; 9(4): 343-348. doi:10.5455/njppp.2019.9.0203416022019



Vancouver/ICMJE Style

Rizvi D, Abidi A, Faiz SM, Hasan R, Thadani A. Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis. Natl J Physiol Pharm Pharmacol. (2019), [cited July 22, 2019]; 9(4): 343-348. doi:10.5455/njppp.2019.9.0203416022019



Harvard Style

Rizvi, D., Abidi, . A., Faiz, . S. M., Hasan, . R. & Thadani, . A. (2019) Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis. Natl J Physiol Pharm Pharmacol, 9 (4), 343-348. doi:10.5455/njppp.2019.9.0203416022019



Turabian Style

Rizvi, Darakhshan, Afroz Abidi, Syed Mohd Faiz, Roohana Hasan, and Anupriya Thadani. 2019. Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis. National Journal of Physiology, Pharmacy and Pharmacology, 9 (4), 343-348. doi:10.5455/njppp.2019.9.0203416022019



Chicago Style

Rizvi, Darakhshan, Afroz Abidi, Syed Mohd Faiz, Roohana Hasan, and Anupriya Thadani. "Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 343-348. doi:10.5455/njppp.2019.9.0203416022019



MLA (The Modern Language Association) Style

Rizvi, Darakhshan, Afroz Abidi, Syed Mohd Faiz, Roohana Hasan, and Anupriya Thadani. "Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis." National Journal of Physiology, Pharmacy and Pharmacology 9.4 (2019), 343-348. Print. doi:10.5455/njppp.2019.9.0203416022019



APA (American Psychological Association) Style

Rizvi, D., Abidi, . A., Faiz, . S. M., Hasan, . R. & Thadani, . A. (2019) Efficacy of curcumin gel and tulsi gel in oral submucous fibrosis. National Journal of Physiology, Pharmacy and Pharmacology, 9 (4), 343-348. doi:10.5455/njppp.2019.9.0203416022019





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