E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Alterations of lipid profile in subclinical hypothyroidism

Vishalaxi Jadhav, Shaktiprasad Hiremath.

Abstract
Background: Thyroid hormones regulate a wide array of metabolic parameters and exert effects virtually on every organ system. Subclinical hypothyroidism is more common than overt hypothyroidism, and an apparently asymptomatic condition defined by slightly increased serum thyrotropin (TSH) concentrations, but normal serum-free T3 and free T4 hormone levels.

Aims and Objectives: The aims of this study were to find a correlation between subclinical hypothyroidism (SCH) and the parameters of lipid profile.

Materials and Methods: Study was carried out in 25 newly diagnosed subclinical hypothyroid subjects and compared with age- and sex-matched controls. Statistical analysis was done using regression analysis with alcula software.

Results: SCH was more common in females and incidence increased as age advanced. Mean cholesterol, total triglycerides (TG), low-density lipoproteins (LDL), and very LDL (VLDL) increased proportionately with TSH level and high-density lipoproteins (HDL) decreased as TSH increased.

Conclusion: SCH appears to be associated with dyslipidemia, that is, increased total cholesterol, TG, LDL, and decreased HDL.

Key words: Subclinical Hypothyroidism; Lipid Profile; Total Cholesterol; Triglycerides; Low-density Lipoproteins; High-density Lipoproteins; Very Low-density Lipoproteins; Dyslipidemia


 
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Pubmed Style

Jadhav V, Hiremath S. Alterations of lipid profile in subclinical hypothyroidism. Natl J Physiol Pharm Pharmacol. 2018; 8(8): 1120-1123. doi:10.5455/njppp.2018.8.0101909042018


Web Style

Jadhav V, Hiremath S. Alterations of lipid profile in subclinical hypothyroidism. http://www.njppp.com/?mno=288225 [Access: August 21, 2018]. doi:10.5455/njppp.2018.8.0101909042018


AMA (American Medical Association) Style

Jadhav V, Hiremath S. Alterations of lipid profile in subclinical hypothyroidism. Natl J Physiol Pharm Pharmacol. 2018; 8(8): 1120-1123. doi:10.5455/njppp.2018.8.0101909042018



Vancouver/ICMJE Style

Jadhav V, Hiremath S. Alterations of lipid profile in subclinical hypothyroidism. Natl J Physiol Pharm Pharmacol. (2018), [cited August 21, 2018]; 8(8): 1120-1123. doi:10.5455/njppp.2018.8.0101909042018



Harvard Style

Jadhav, V. & Hiremath, S. (2018) Alterations of lipid profile in subclinical hypothyroidism. Natl J Physiol Pharm Pharmacol, 8 (8), 1120-1123. doi:10.5455/njppp.2018.8.0101909042018



Turabian Style

Jadhav, Vishalaxi, and Shaktiprasad Hiremath. 2018. Alterations of lipid profile in subclinical hypothyroidism. National Journal of Physiology, Pharmacy and Pharmacology, 8 (8), 1120-1123. doi:10.5455/njppp.2018.8.0101909042018



Chicago Style

Jadhav, Vishalaxi, and Shaktiprasad Hiremath. "Alterations of lipid profile in subclinical hypothyroidism." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 1120-1123. doi:10.5455/njppp.2018.8.0101909042018



MLA (The Modern Language Association) Style

Jadhav, Vishalaxi, and Shaktiprasad Hiremath. "Alterations of lipid profile in subclinical hypothyroidism." National Journal of Physiology, Pharmacy and Pharmacology 8.8 (2018), 1120-1123. Print. doi:10.5455/njppp.2018.8.0101909042018



APA (American Psychological Association) Style

Jadhav, V. & Hiremath, S. (2018) Alterations of lipid profile in subclinical hypothyroidism. National Journal of Physiology, Pharmacy and Pharmacology, 8 (8), 1120-1123. doi:10.5455/njppp.2018.8.0101909042018





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