E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


A study to access impairment of autonomic nervous system in obesity

Naushi Mujeeb.

Abstract
Background: Obesity which is itself a significant health hazard is also associated with dysfunctioning of autonomic nervous system (ANS).

Aims and Objective: This study was conducted to assess autonomic dysfunction in obese and compare it with age-matched controls.

Materials and Methods: The study group consisted of 55 healthy obese people (median 35 ± 6.0 years of age) and the control group consisted of 55 healthy non-obese people (median 31 ± 5.2 years). Six non-invasive autonomic function tests were performed out of which four were based mainly on parasympathetic control heart rate response to standing (30:15 ratio). The standing to lying ratio, Valsalva ratio, and the resting heart rate and the other two tests were based on sympathetic control (isometric handgrip exercise test systolic blood pressure (SBP) and cold-pressor test SBP, and diastolic BP).

Results: Present study showed significantly lower values (P ≤ 0.005) for the parasympathetic tests in the study group when compared to controls indicating impaired parasympathetic function. Similarly, the findings of sympathetic tests in study groups were significantly less (P ≤ 0.005) as compared to the controls indicating impaired sympathetic function.

Conclusion: Thus, in obesity activity of both sympathetic as well as parasympathetic divisions of ANS (autonomic nervous system) are affected, which may be the cause of various complications associated with obesity.

Key words: Autonomic Nervous System; Body Mass Index; Obesity; Valsalva Maneuver


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Naushi Mujeeb
on Google
on Google Scholar
Article Statistics
 Viewed: 310
Downloaded: 135
Cited: 0

How to Cite this Article
Pubmed Style

Naushi Mujeeb. A study to access impairment of autonomic nervous system in obesity. Natl J Physiol Pharm Pharmacol. 2018; 8(4): 475-478. doi:10.5455/njppp.2017.7.1143216112017


Web Style

Naushi Mujeeb. A study to access impairment of autonomic nervous system in obesity. http://www.njppp.com/?mno=283030 [Access: April 22, 2018]. doi:10.5455/njppp.2017.7.1143216112017


AMA (American Medical Association) Style

Naushi Mujeeb. A study to access impairment of autonomic nervous system in obesity. Natl J Physiol Pharm Pharmacol. 2018; 8(4): 475-478. doi:10.5455/njppp.2017.7.1143216112017



Vancouver/ICMJE Style

Naushi Mujeeb. A study to access impairment of autonomic nervous system in obesity. Natl J Physiol Pharm Pharmacol. (2018), [cited April 22, 2018]; 8(4): 475-478. doi:10.5455/njppp.2017.7.1143216112017



Harvard Style

Naushi Mujeeb (2018) A study to access impairment of autonomic nervous system in obesity. Natl J Physiol Pharm Pharmacol, 8 (4), 475-478. doi:10.5455/njppp.2017.7.1143216112017



Turabian Style

Naushi Mujeeb. 2018. A study to access impairment of autonomic nervous system in obesity. National Journal of Physiology, Pharmacy and Pharmacology, 8 (4), 475-478. doi:10.5455/njppp.2017.7.1143216112017



Chicago Style

Naushi Mujeeb. "A study to access impairment of autonomic nervous system in obesity." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 475-478. doi:10.5455/njppp.2017.7.1143216112017



MLA (The Modern Language Association) Style

Naushi Mujeeb. "A study to access impairment of autonomic nervous system in obesity." National Journal of Physiology, Pharmacy and Pharmacology 8.4 (2018), 475-478. Print. doi:10.5455/njppp.2017.7.1143216112017



APA (American Psychological Association) Style

Naushi Mujeeb (2018) A study to access impairment of autonomic nervous system in obesity. National Journal of Physiology, Pharmacy and Pharmacology, 8 (4), 475-478. doi:10.5455/njppp.2017.7.1143216112017





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • How to write a thesis? [English]
    Swapnil s Agarwal, Preeti Yadav, Krishnadutt Chavali, Lavlesh Kumar
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 86-90
    » Abstract

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Prophylaxis and Treatment for Leptospirosis: Where are the Evidences?
    Jaykaran Charan, Deepak Saxena, Summaiya Mulla
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 78-83
    » Abstract & References » doi: 10.5455/njppp.2012.2.78-83

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20

  • Antidiabetic activity of alcoholic extract of Neem (Azadirachta Indica) root bark
    Prabhakar Patil, Sudha Patil, Abhay Mane, Sushilkumar Verma
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 142-146
    » Abstract & References » doi: 10.5455/njppp.2013.3.134-138

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Most Cited Articles
  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 8 times [Click to see citing articles]

  • A pilot study to evaluate the effect of HAART on gonadal dysfunction in male HIV patients
    Abhishek Pathak, Lalit Prashant Meena, Jaya Chakravarty, Madhukar Rai, Shyam Sundar
    Natl J Physiol Pharm Pharmacol. 2015; 5(1): 33-35
    » Abstract & References » doi: 10.5455/njppp.2015.5.120720142
    Cited : 6 times [Click to see citing articles]

  • Newer anti-platelet and anti-thrombotic drugs on the horizon
    Ajai Garg, Anjana Pandey, Pranab Oza, Mridul Chaturvedi
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 105-110
    » Abstract & References » doi: 10.5455/njppp.2013.3.090420131
    Cited : 5 times [Click to see citing articles]

  • Rate pressure product predicts cardiovascular risk in type 2 diabetics with cardiac autonomic neuropathy
    Rishu Segan, Vidushi Gupta, Lily Walia, Naveen Mittal
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 43-47
    » Abstract & References » doi: 10.5455/njppp.2013.3.43-47
    Cited : 4 times [Click to see citing articles]

  • Effects of sixteen weeks exercise training on left ventricular dimensions and function in young athletes
    Sandip M Hulke, Yuganti P Vaidya, Amandeepkour R Ratta
    Natl J Physiol Pharm Pharmacol. 2012; 2(2): 152-158
    » Abstract & References » doi: 10.5455/njppp.2012.2.152-158
    Cited : 4 times [Click to see citing articles]

  • Prevalence and risk factors for eating disorders in Indian adolescent females
    Amit A Upadhyah, Rajesh Misra, Deepak N Parchwani, Pankaj B Maheria
    Natl J Physiol Pharm Pharmacol. 2014; 4(2): 153-157
    » Abstract & References » doi: 10.5455/njppp.2014.4.041220131
    Cited : 4 times [Click to see citing articles]

  • Time domain measures of heart rate variability during acute mental stress in Type 2 diabetics- A case control study
    Anupama Deepak, Deepak A N, Shobha Nallulwar, Vitthal Khode
    Natl J Physiol Pharm Pharmacol. 2014; 4(1): 34-38
    » Abstract & References » doi: 10.5455/njppp.2014.4.080720131
    Cited : 4 times [Click to see citing articles]

  • Ratio of second to fourth digit as a predictor of performance in elite Indian volley ball players
    Kaninika Panda, Pralay Majumdar, Veena Umesh, HH Sudhakar
    Natl J Physiol Pharm Pharmacol. 2014; 4(2): 106-108
    » Abstract & References » doi: 10.5455/njppp.2014.4.011020132
    Cited : 4 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimer’s disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 4 times [Click to see citing articles]

  • Second MBBS medical student’s feedback on teaching methodology and evaluation methods in Pharmacology
    Nilesh Chavda, Preeti Yadav, Jay Karan, N. D. Kantharia
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 23-31
    » Abstract & References » doi: 10.5455/njppp.2011.1.23-31
    Cited : 3 times [Click to see citing articles]