E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study

Pallavi Kulkarni, Alice Kuruvilla, Regina Roy.

Abstract
Background: Although antibiotics are the mainstay of treatment for urinary tract infections (UTIs), in view of growing antibiotic resistance, role of supportive drugs in the management of UTI cannot be ignored especially those requiring hospital care.

Aims and Objective: The aim of the study was to assess the pattern of supportive drugs used in the management of UTIs in hospital settings.

Materials and Methods: This was a prospective observational study, 80 patients above the age of 18 years, admitted to the hospital with UTI were included in the study. Their case records were evaluated to know the pattern of supportive drugs. The patients were assessed for the clinical and bacteriological outcome at the end of treatment. The data were analyzed using descriptive statistics, namely mean and standard deviation.

Results: Mean age of presentation was 51.25 ± 12.7 years with 59% females (n = 47) and 41% males (n=33). Lower UTI (n = 58, 73%) was more common than upper UTI (n = 16, 20%). Analgesics and antipyretics (paracetamol: 32, 40%; diclofenac: 40, 50%; and tramadol: 20, 25%) were the most common supportive drugs. 74 patients (93%) received urinary alkalizers (sodium/potassium citrate). Antispasmodics (flavoxate: 27, 34%; oxybutynin: 8, 10%; and darifenacin: 7, 9%) and alpha-blockers (tamsulosin: 8, 10%; alfuzosin: 15, 19%; and doxazosin: 4, 5%) were used in subgroup of patients. Acid suppressants (proton pump inhibitors: 41, 51% and ranitidine: 22, 28%) and antiemetics (ondansetron: 34, 43%) were used in patients with gastric distress. 95% (n = 76) had clinical cure and 39% (n = 31) had bacteriological cure at the end of treatment.

Conclusion: Appropriate supportive drugs when used along with antibiotics, can have a potential for rapid symptom relief, hasten recovery, may reduce duration of hospital stay and thus aid for more efficient and complete management.

Key words: Urinary Tract Infection; Antibiotics; Analgesics; Supportive Drugs


 
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Pubmed Style

Kulkarni P, Kuruvilla A, Roy R. Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study. Natl J Physiol Pharm Pharmacol. 2019; 9(4): 299-302. doi:10.5455/njppp.2019.9.0102206022019


Web Style

Kulkarni P, Kuruvilla A, Roy R. Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study. http://www.njppp.com/?mno=27793 [Access: July 22, 2019]. doi:10.5455/njppp.2019.9.0102206022019


AMA (American Medical Association) Style

Kulkarni P, Kuruvilla A, Roy R. Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study. Natl J Physiol Pharm Pharmacol. 2019; 9(4): 299-302. doi:10.5455/njppp.2019.9.0102206022019



Vancouver/ICMJE Style

Kulkarni P, Kuruvilla A, Roy R. Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study. Natl J Physiol Pharm Pharmacol. (2019), [cited July 22, 2019]; 9(4): 299-302. doi:10.5455/njppp.2019.9.0102206022019



Harvard Style

Kulkarni, P., Kuruvilla, . A. & Roy, . R. (2019) Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study. Natl J Physiol Pharm Pharmacol, 9 (4), 299-302. doi:10.5455/njppp.2019.9.0102206022019



Turabian Style

Kulkarni, Pallavi, Alice Kuruvilla, and Regina Roy. 2019. Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study. National Journal of Physiology, Pharmacy and Pharmacology, 9 (4), 299-302. doi:10.5455/njppp.2019.9.0102206022019



Chicago Style

Kulkarni, Pallavi, Alice Kuruvilla, and Regina Roy. "Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 299-302. doi:10.5455/njppp.2019.9.0102206022019



MLA (The Modern Language Association) Style

Kulkarni, Pallavi, Alice Kuruvilla, and Regina Roy. "Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study." National Journal of Physiology, Pharmacy and Pharmacology 9.4 (2019), 299-302. Print. doi:10.5455/njppp.2019.9.0102206022019



APA (American Psychological Association) Style

Kulkarni, P., Kuruvilla, . A. & Roy, . R. (2019) Role of supportive drugs in the management of urinary tract infections in hospital settings - A prospective observational study. National Journal of Physiology, Pharmacy and Pharmacology, 9 (4), 299-302. doi:10.5455/njppp.2019.9.0102206022019





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