E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market

Anuradha S Joshi, Rajvi K Shah, Mona H Suthar, Unnati H Keharia.

Abstract
Background: Literature reports growing concern on ever-burgeoning list of irrational fixed dose combinations (FDCs) flooding the Indian market. Current study addresses availability and rationality of two most common group of FDC used clinically, that is, antimicrobial (AM) and antidiarrheal (AD).

Aim and Objective: Analysis of rationality of AM and AD, FDCs, and available in Indian market.

Materials and Methods: AM and AD, FDCs listed in Indian Drug Review 2017 and 2018, were analyzed using a validated eight- point criteria tool.

Results: Out of 138 FDCs, 102 (73.91%) belonged to AM group and 36 (26.08%) belonged to AD group. Out of 102 AM FDCs, 46 (45.09%) were rational and 56 (54.90%) were irrational. Out of 36 AD, FDCs, 10 (27.77%) were rational and 26 (72.22%) were irrational. Mean rationality score of AM and AD, FDCs, was (7.72 0.33) and (7.5 0.78), respectively.

Conclusion: Analysis reveals that a number of FDCs available in Indian market is irrational.

Key words: Fixed Dose Combination; Antimicrobial; Antidiarrheal; Irrational; Indian Market


 
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How to Cite this Article
Pubmed Style

Joshi AS, Shah RK, Suthar MH, Keharia UH. Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market. Natl J Physiol Pharm Pharmacol. 2021; 11(2): 222-226. doi:10.5455/njppp.2021.11.12360202025122020


Web Style

Joshi AS, Shah RK, Suthar MH, Keharia UH. Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market. http://www.njppp.com/?mno=27726 [Access: February 01, 2021]. doi:10.5455/njppp.2021.11.12360202025122020


AMA (American Medical Association) Style

Joshi AS, Shah RK, Suthar MH, Keharia UH. Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market. Natl J Physiol Pharm Pharmacol. 2021; 11(2): 222-226. doi:10.5455/njppp.2021.11.12360202025122020



Vancouver/ICMJE Style

Joshi AS, Shah RK, Suthar MH, Keharia UH. Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market. Natl J Physiol Pharm Pharmacol. (2021), [cited February 01, 2021]; 11(2): 222-226. doi:10.5455/njppp.2021.11.12360202025122020



Harvard Style

Joshi, A. S., Shah, . R. K., Suthar, . M. H. & Keharia, . U. H. (2021) Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market. Natl J Physiol Pharm Pharmacol, 11 (2), 222-226. doi:10.5455/njppp.2021.11.12360202025122020



Turabian Style

Joshi, Anuradha S, Rajvi K Shah, Mona H Suthar, and Unnati H Keharia. 2021. Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market. National Journal of Physiology, Pharmacy and Pharmacology, 11 (2), 222-226. doi:10.5455/njppp.2021.11.12360202025122020



Chicago Style

Joshi, Anuradha S, Rajvi K Shah, Mona H Suthar, and Unnati H Keharia. "Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market." National Journal of Physiology, Pharmacy and Pharmacology 11 (2021), 222-226. doi:10.5455/njppp.2021.11.12360202025122020



MLA (The Modern Language Association) Style

Joshi, Anuradha S, Rajvi K Shah, Mona H Suthar, and Unnati H Keharia. "Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market." National Journal of Physiology, Pharmacy and Pharmacology 11.2 (2021), 222-226. Print. doi:10.5455/njppp.2021.11.12360202025122020



APA (American Psychological Association) Style

Joshi, A. S., Shah, . R. K., Suthar, . M. H. & Keharia, . U. H. (2021) Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market. National Journal of Physiology, Pharmacy and Pharmacology, 11 (2), 222-226. doi:10.5455/njppp.2021.11.12360202025122020