E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Effect of age and gender on QT interval

Sudeep Satpathy, Smita Satpathy, Prakash Kumar Nayak.

Abstract
Background: The sudden cardiac death syndrome has a large preponderance in men compared to women and that too in older age group. Various population studies have demonstrated four- to seven-fold increase of sudden cardiac death among men compared with women. As coronary event risk increases in post-menopausal women, sudden cardiac death risk increases proportionately. Corrected QT interval measurements may predict the chances of increased risk of sudden cardiac death in an apparently healthy individual.

Aims and Objectives: The objective of the study was to find any independent association between age and gender on the QT-corrected interval.

Materials and Methods: This study included 48 healthy men and 32 healthy women between 17 and 68 years age divided into three groups: Young (<30 years), middle-aged (30-60 years), and the elderly (>60 years). Standard supine 12 lead electrocardiographic was done in these subjects, and statistical analysis was done. The cutoff points for QTc were ≤450 ms (normal), 451 to 470 ms (borderline), and >470 ms (prolonged), in case of women, and ≤430 ms (normal), 431 to 450 ms (borderline), and >450 ms (prolonged) for men.

Results: QTc was found to be 374.9 31 (ms) in the young group, 386.3 14.8 (ms) in middle-aged group, and 414.5 11.8 (ms) in the elderly group. Males had longer QTc than the females in the young- and the middle-age groups.

Conclusion: Age significantly correlated (r = 0.475) with QT and QTc interval in healthy subjects. Gender was a poor predictor of QT interval.

Key words: Age; Gender; QT Interval; QT-corrected Interval


 
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Pubmed Style

Satpathy S, Satpathy S, Nayak PK. Effect of age and gender on QT interval. Natl J Physiol Pharm Pharmacol. 2018; 8(2): 224-227. doi:10.5455/njppp.2018.8.0832304092017


Web Style

Satpathy S, Satpathy S, Nayak PK. Effect of age and gender on QT interval. http://www.njppp.com/?mno=275621 [Access: July 16, 2018]. doi:10.5455/njppp.2018.8.0832304092017


AMA (American Medical Association) Style

Satpathy S, Satpathy S, Nayak PK. Effect of age and gender on QT interval. Natl J Physiol Pharm Pharmacol. 2018; 8(2): 224-227. doi:10.5455/njppp.2018.8.0832304092017



Vancouver/ICMJE Style

Satpathy S, Satpathy S, Nayak PK. Effect of age and gender on QT interval. Natl J Physiol Pharm Pharmacol. (2018), [cited July 16, 2018]; 8(2): 224-227. doi:10.5455/njppp.2018.8.0832304092017



Harvard Style

Satpathy, S., Satpathy, S. & Nayak, P. K. (2018) Effect of age and gender on QT interval. Natl J Physiol Pharm Pharmacol, 8 (2), 224-227. doi:10.5455/njppp.2018.8.0832304092017



Turabian Style

Satpathy, Sudeep, Smita Satpathy, and Prakash Kumar Nayak. 2018. Effect of age and gender on QT interval. National Journal of Physiology, Pharmacy and Pharmacology, 8 (2), 224-227. doi:10.5455/njppp.2018.8.0832304092017



Chicago Style

Satpathy, Sudeep, Smita Satpathy, and Prakash Kumar Nayak. "Effect of age and gender on QT interval." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 224-227. doi:10.5455/njppp.2018.8.0832304092017



MLA (The Modern Language Association) Style

Satpathy, Sudeep, Smita Satpathy, and Prakash Kumar Nayak. "Effect of age and gender on QT interval." National Journal of Physiology, Pharmacy and Pharmacology 8.2 (2018), 224-227. Print. doi:10.5455/njppp.2018.8.0832304092017



APA (American Psychological Association) Style

Satpathy, S., Satpathy, S. & Nayak, P. K. (2018) Effect of age and gender on QT interval. National Journal of Physiology, Pharmacy and Pharmacology, 8 (2), 224-227. doi:10.5455/njppp.2018.8.0832304092017





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