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Case Report Open Access


Clonazepam-induced acute liver injury: A case report

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M.

Abstract
Clonazepam belongs to the benzodiazepine class of drugs (benzodiazepine derivative). It is used both as an anticonvulsant and in the treatment of panic disorder with or without agoraphobia. The most frequent adverse drug reactions of clonazepam are sedation or drowsiness, ataxia or hypotonia, and behavioral disturbances. Hepatomegaly and transient elevations in serum aminotransferases and alkaline phosphatase concentrations may occur in patients receiving this drug, but the frequency of the reaction has not been well defined. Here, we report that an acute psychosis case was the patientís laboratory reports showed a transient elevation in serum transaminases and alkaline phosphatase levels after clonazepam was administered.

Key words: Clonazepam; Benzodiazepines; Serum Transaminases; Alkaline Phosphatase; Adverse Drug Reaction


 
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How to Cite this Article
Pubmed Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017


Web Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. http://www.njppp.com/?mno=271177 [Access: December 18, 2017]. doi:10.5455/njppp.2017.7.0723308072017


AMA (American Medical Association) Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017



Vancouver/ICMJE Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. (2017), [cited December 18, 2017]; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017



Harvard Style

Nair, M. M., Abraham, D. S. & M, N. C. (2017) Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017



Turabian Style

Nair, Malini Muraleedharan, Dhanya Susan Abraham, and Neethu C M. 2017. Clonazepam-induced acute liver injury: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017



Chicago Style

Nair, Malini Muraleedharan, Dhanya Susan Abraham, and Neethu C M. "Clonazepam-induced acute liver injury: A case report." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017



MLA (The Modern Language Association) Style

Nair, Malini Muraleedharan, Dhanya Susan Abraham, and Neethu C M. "Clonazepam-induced acute liver injury: A case report." National Journal of Physiology, Pharmacy and Pharmacology 7.12 (2017), 1439-1440. Print. doi:10.5455/njppp.2017.7.0723308072017



APA (American Psychological Association) Style

Nair, M. M., Abraham, D. S. & M, N. C. (2017) Clonazepam-induced acute liver injury: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017



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